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Low-dose environmental radiation, DNA damage, and cancer: The possible contribution of psychological factors
- Source :
- Psychology, Health & Medicine. 15:1-16
- Publication Year :
- 2010
- Publisher :
- Informa UK Limited, 2010.
-
Abstract
- Radiation causes DNA damage, increases risk of cancer, and is associated with psychological stress responses. This article proposes an evidence-based integrative model in which psychological factors could interact with radiation by either augmenting or moderating the adverse effects of radiation on DNA integrity and eventual tumorigenesis. Based on a review of the literature, we demonstrate the following: (1) the effects of low-dose radiation exposures on DNA integrity and on tumorigenesis; (2) the effects of low-dose radiation exposure on psychological distress; (3) the relationship between psychological factors and DNA damage; and (4) the possibility that psychological stress augments and that psychological resource variables moderate radiation-induced DNA damage and risk of cancer. The additional contribution of psychological processes to radiation-DNA damage-cancer relationships needs further study, and if verified, has clinical implications.
- Subjects :
- Oncology
medicine.medical_specialty
Neoplasms, Radiation-Induced
DNA damage
psychological factors
medicine.disease_cause
Developmental psychology
Dose-Response Relationship
Internal medicine
medicine
Humans
Psychological stress
Risk factor
Adverse effect
Applied Psychology
Cancer
Low dose
Dose-Response Relationship, Radiation
Psychoneuroimmunology
DNA
Environmental Exposure
Environmental exposure
medicine.disease
Psychiatry and Mental health
Clinical Psychology
radiation effects
Carcinogenesis
Psychology
Stress, Psychological
DNA Damage
Subjects
Details
- ISSN :
- 14653966 and 13548506
- Volume :
- 15
- Database :
- OpenAIRE
- Journal :
- Psychology, Health & Medicine
- Accession number :
- edsair.doi.dedup.....a15d140c856982641771feaa8c78725a