Circulating dipeptidyl peptidase-4 activity is associated with insulin resistance in type 1 diabetic patients

Authors :: Kristina Blaslov
Lea Duvnjak
Tomislav Bulum
Source :: Journal of Diabetes and its Complications. 29:390-394
Publication Year :: 2015
Publisher :: Elsevier BV, 2015.
Abstract: AIM: The pathophysiology of insulin resistance (IR) comprises a complex adipokine mediated cross-talk between white adipose tissue and other organs. Dipeptidyl peptidase-4 (DPP4) is protease recently proposed as a novel adipokine linked to IR. We aimed to assess the relationship between fasting serum DPP4 activityand IR in type 1 diabetic (T1DM) patients. ----- METHODS: A cross-sectional study comprised 44 T1DM patients aged >18 and

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