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Accuracy of technetium-99m sestamibi scintimammography and X-ray mammography in premenopausal women with suspected breast cancer
- Source :
- European Journal of Nuclear Medicine. 28:1776-1780
- Publication Year :
- 2001
- Publisher :
- Springer Science and Business Media LLC, 2001.
-
Abstract
- The aim of this study was to evaluate the usefulness of technetium-99m sestamibi scintimammography (SSM) and combined use of SSM and X-ray mammography (MG) in premenopausal patients with small (≤2 cm) suspicious breast lesions. Eighty-seven premenopausal women (median age 47 years, range 32–52) with breast lesions ranging from 4 to 20 mm in greatest diameter (median 12 mm) and detected by MG, underwent SSM prior to open breast biopsy. A planar camera and single-photon emission tomography (SPET) technique were used in 23 (26.4%) and 64 (73.6%) patients, respectively. At histological examination, 72 (82.8%) breast cancers (pT1a=3, pT1b=27, pT1c=42) and 15 (17.2%) benign masses were found. Sensitivity, specificity, positive predictive value, negative predictive value and accuracy of MG and SSM were 80.6% vs 80.6%, 60.0% vs 93.3% (P
- Subjects :
- Technetium Tc 99m Sestamibi
mammography
Mammary gland
Breast cancer, scintimammography, breast, cancer, early breast cancer, breast diseases, malignancy, menopause, premenopausal, estrogen receptors, mammography, dense breast, 99mTc, SPET, MIBI, mammography, sensitivity, specificity
menopause
specificity
Breast Neoplasms
Scintigraphy
Sensitivity and Specificity
Technetium (99mTc) sestamibi
Isotopes of technetium
Breast cancer
Predictive Value of Tests
Carcinoma
medicine
Humans
cancer
Mammography
Radiology, Nuclear Medicine and imaging
MIBI
early breast cancer
breast
99mTc
Tomography, Emission-Computed, Single-Photon
breast diseases
Scintimammography
scintimammography
premenopausal
medicine.diagnostic_test
business.industry
estrogen receptors
General Medicine
Middle Aged
sensitivity
medicine.disease
SPET
medicine.anatomical_structure
Premenopause
Female
dense breast
Radiopharmaceuticals
business
Nuclear medicine
malignancy
medicine.drug
Subjects
Details
- ISSN :
- 16197089 and 16197070
- Volume :
- 28
- Database :
- OpenAIRE
- Journal :
- European Journal of Nuclear Medicine
- Accession number :
- edsair.doi.dedup.....a111b435534c656e654d2dff32a5b76d