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Nonequilibrium Green's functions for functional connectivity in the brain
- Source :
- Physical review letters
- Publication Year :
- 2020
-
Abstract
- A theoretical framework describing the set of interactions between neurons in the brain, or functional connectivity, should include dynamical functions representing the propagation of signal from one neuron to another. Green's functions and response functions are natural candidates for this but, while they are conceptually very useful, they are usually defined only for linear time-translationally invariant systems. The brain, instead, behaves nonlinearly and in a time-dependent way. Here, we use nonequilibrium Green's functions to describe the time-dependent functional connectivity of a continuous-variable network of neurons. We show how the connectivity is related to the measurable response functions, and provide two illustrative examples via numerical calculations, inspired from $\textit{C. elegans}$.<br />6 pages (incl. bibliography), 2 figures + supplement (6 pages)
- Subjects :
- Computer science
Models, Neurological
General Physics and Astronomy
Non-equilibrium thermodynamics
Cell Communication
01 natural sciences
Article
Green S
chemistry.chemical_compound
0103 physical sciences
Connectome
Animals
Invariant (mathematics)
Mathematics::Representation Theory
Caenorhabditis elegans
010306 general physics
Set (psychology)
Computational Neuroscience
Neurons
Quantitative Biology::Neurons and Cognition
Functional connectivity
SIGNAL (programming language)
Brain
Quantitative Biology::Genomics
Networks, dynamical systems
chemistry
FOS: Biological sciences
Quantitative Biology - Neurons and Cognition
Computer Science::Programming Languages
Neurons and Cognition (q-bio.NC)
Nerve Net
Biological system
Subjects
Details
- Language :
- English
- Database :
- OpenAIRE
- Journal :
- Physical review letters
- Accession number :
- edsair.doi.dedup.....a0fd94142b7fff36d2bbffeb0530727f