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Markers of Myocardial Damage in Children of the First Year of Life with Congenital Heart Disease in the Early Period after Surgery with Cardioplegic Anoxia
- Source :
- Bulletin of Experimental Biology and Medicine. 158:421-424
- Publication Year :
- 2015
- Publisher :
- Springer Science and Business Media LLC, 2015.
-
Abstract
- We measured the level of cardiac markers (high-sensitivity troponin T and MB fraction of creatine kinase) in children of the first year of life with congenital heart disease in the perioperative period. After cardiac surgery, plasma levels of the above markers exceed the reference limits in the examined children. The diagnosis of myocardial ischemia using biochemical markers in the postoperative period is possible only by dynamic monitoring of the cardiac marker level. The preoperative concentration of high-sensitivity troponin T in children of the first year of life with congenital heart disease can be regarded as a predictor of postoperative complications.
- Subjects :
- Heart Defects, Congenital
medicine.medical_specialty
Heart disease
Period (gene)
Cardiac marker
Myocardial Ischemia
First year of life
General Biochemistry, Genetics and Molecular Biology
Troponin T
Internal medicine
medicine
Creatine Kinase, MB Form
Humans
Hypoxia
biology
business.industry
Infant
General Medicine
Perioperative
medicine.disease
Cardiac surgery
Surgery
ROC Curve
Area Under Curve
Heart Arrest, Induced
biology.protein
Cardiology
Creatine kinase
business
Biomarkers
Subjects
Details
- ISSN :
- 15738221 and 00074888
- Volume :
- 158
- Database :
- OpenAIRE
- Journal :
- Bulletin of Experimental Biology and Medicine
- Accession number :
- edsair.doi.dedup.....a0f5caea01d1c91f116b37762cd1279c