Back to Search
Start Over
Estrogen receptors in human pulp tissue
- Source :
- Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics. 95(3)
- Publication Year :
- 2003
-
Abstract
- Objective. The aim of this study was to evaluate the expression of estrogen receptor (ER)-α in human pulp tissue. Study Design. Tissue samples were collected from 51 teeth extracted for orthodontic reasons or from endodontically treated teeth. Immunohistochemical staining was performed with mouse antihuman ER-α 1D5 by using the alkaline phosphatase antialkaline phosphatase technique. Immunohistochemical reactivity was semiquantitatively assessed and graded on an intensity scale of 0 to 3. Results. ERs were found in odontoblasts, endothelial cells, and Schwann cells. By means of statistical analysis, ERs were found to be common in odontoblasts (1.3-1.6) and in endothelial cells (1.0-1.4), whereas in Schwann cells they were somewhat rare (0.7-1.1). Difference in expression of ERs was not found among patients in different age groups. With respect to sex, a difference in reactivity was observed in Schwann cells, which showed higher reactivity in female pulps. Conclusion. The results of this study confirm the expression of ER-α in the human dental pulp. (Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2003;95:340-4)
- Subjects :
- Adult
Male
Pathology
medicine.medical_specialty
human dental pulp
estrogen receptors
odontoblasts
endothelial cells
Schwann cells
Phosphatase
Estrogen receptor
Immunoenzyme Techniques
stomatognathic system
Oral administration
Biopsy
Medicine
Humans
Endothelium
General Dentistry
Dental Pulp
Menstrual Cycle
medicine.diagnostic_test
Odontoblasts
business.industry
stomatognathic diseases
Odontoblast
Otorhinolaryngology
Receptors, Estrogen
Pulp (tooth)
Immunohistochemistry
Alkaline phosphatase
Surgery
Female
Schwann Cells
Oral Surgery
business
Subjects
Details
- ISSN :
- 10792104
- Volume :
- 95
- Issue :
- 3
- Database :
- OpenAIRE
- Journal :
- Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics
- Accession number :
- edsair.doi.dedup.....a0eda53e74c6053d011e8ae9043ae879