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Extrapulmonary Pneumocystis carinii infections

Extrapulmonary Pneumocystis carinii infections

Authors :
Jonathan W. M. Gold
Richard J. Cote
Donald Armstrong
Edward E. Telzak
Suzanne Wise Campbell
Source :
Reviews of infectious diseases. 12(3)
Publication Year :
1990

Abstract

A case of disseminated infection with Pneumocystis carinii is presented, and the Englishlanguage literature is reviewed for cases of documented extrapulmonary infection with this organism. In this case- with P. carinii diffusely replacing the bone marrow and causing hepatic, adrenal, and glomerular tuft necrosis - the clinical illness and multiple-organ dysfunction attributed to disseminated P carinii were more severe than had previously been described. Because the rate of extrapulmonary R carinii infection found at autopsy in patients with AIDS is at least 2.5% at our institution, we caution against the routine use of aerosol rather than parenteral pentamidine for treatment of P carinii pneumonia until additional data are available. Pneumocystis carinii is the most common agent causing opportunistic infection in patients with AIDS. Over 60% of patients with AIDS reported to the Centers for Disease Control have presented with P carinii pneumonia (PCP) as their initial op

Details

ISSN :
01620886
Volume :
12
Issue :
3
Database :
OpenAIRE
Journal :
Reviews of infectious diseases
Accession number :
edsair.doi.dedup.....a0cf61d70275759771045045fed40a82