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Size of sentinel-node metastasis and chances of non-sentinel-node involvement and survival in early stage vulvar cancer: results from GROINSS-V, a multicentre observational study
- Source :
- The Lancet Oncology, 11(7), 646-652, Lancet Oncology, 11(7), 646-652. Lancet Publishing Group, Lancet Oncology, 11, 646-52, Lancet Oncology, 11(7), 646-652. ELSEVIER SCIENCE INC, Lancet Oncology, 11, 7, pp. 646-52, lancet oncology, 11(7), 646-652. Lancet Publishing Group, Oonk, M H, van Hemel, B M, Hollema, H, de Hullu, J A, Ansink, AC, Vergote, I, Verheijen, R H M, Maggioni, A, Gaarenstroom, K N, Baldwin, P J, van Dorst, E B, van der Velden, J, Hermans, R H, van der Putten, H W, Drouin, P, Runnebaum, I B, Sluiter, W J & van der Zee, A G 2010, ' Size of sentinel-node metastasis and chances of non-sentinel-node involvement and survival in early stage vulvar cancer: results from GROINSS-V, a multicentre observational study ', Lancet Oncology, vol. 11, no. 7, pp. 646-652 . https://doi.org/10.1016/S1470-2045(10)70104-2
- Publication Year :
- 2010
-
Abstract
- Contains fulltext : 89256.pdf (Publisher’s version ) (Closed access) BACKGROUND: Currently, all patients with vulvar cancer with a positive sentinel node undergo inguinofemoral lymphadenectomy, irrespective of the size of sentinel-node metastases. Our study aimed to assess the association between size of sentinel-node metastasis and risk of metastases in non-sentinel nodes, and risk of disease-specific survival in early stage vulvar cancer. METHODS: In the GROningen INternational Study on Sentinel nodes in Vulvar cancer (GROINSS-V), sentinel-node detection was done in patients with T1-T2 (
- Subjects :
- Oncology
medicine.medical_specialty
Sentinel lymph node
MELANOMA
Aetiology, screening and detection [ONCOL 5]
Groin
Disease-Free Survival
Metastasis
SDG 3 - Good Health and Well-being
Internal medicine
Secondary Prevention
medicine
Humans
BREAST-CANCER
Survival rate
squamous-cell carcinoma breast-cancer lymph-nodes micrometastases melanoma
Aged
Proportional Hazards Models
Cancer staging
LYMPH-NODES
Vulvar Neoplasms
Sentinel Lymph Node Biopsy
business.industry
Melanoma
Sentinel node
Vulvar cancer
Prognosis
medicine.disease
Survival Analysis
MICROMETASTASES
Inguinofemoral Lymphadenectomy
Lymphatic Metastasis
Female
SQUAMOUS-CELL CARCINOMA
Neoplasm Recurrence, Local
business
Subjects
Details
- ISSN :
- 14702045
- Volume :
- 11
- Issue :
- 7
- Database :
- OpenAIRE
- Journal :
- Lancet Oncology
- Accession number :
- edsair.doi.dedup.....a0cba83157af3d013cdf0d8369bac42d