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Recognition of category-related visual stimuli in Parkinson's disease: before and after pharmacological treatment
- Source :
- Università degli studi di Firenze-IRIS
- Publication Year :
- 2006
-
Abstract
- Visual-sensory dysfunctions and semantic processing impairments are widely reported in Parkinson's disease (PD) research. The present study investigated the category-specific deficit in object recognition as a function of both the semantic category and spatial frequency content of stimuli. In the first experiment, the role of dopamine in object-recognition processing was assessed by comparing PD drug naive (PD-DN), PD receiving levodopa treatment (PD-LD), and control subjects. Experiment 2 consisted of a retest session for PD drug naive subjects after a period of pharmacological treatment. All participants completed an identification task which displayed animals and tools at nine levels of filtering. Each object was revealed in a sequence of frames whereby the object was presented at increasingly less-filtered images up to a complete version of the image. Results indicate an impaired identification pattern for PD-DN subjects solely for animal category stimuli. This differential pharmacological therapy effect was also confirmed at retest (experiment 2). Thus, our data suggest that dopaminergic loss has a specific role in category-specific impairment. Two possible hypotheses are discussed that may account for the defective recognition of semantically different objects in PD.
- Subjects :
- Male
Levodopa
Parkinson's disease
Visual perception
Cognitive Neuroscience
Dopamine
Experimental and Cognitive Psychology
Statistics, Nonparametric
Antiparkinson Agents
Contrast Sensitivity
Behavioral Neuroscience
Form perception
Reference Values
medicine
Semantic memory
Humans
Aged
Analysis of Variance
Memoria
Parkinson Disease
Recognition, Psychology
Middle Aged
medicine.disease
Classification
Form Perception
Drug-naïve
Categorization
Case-Control Studies
Female
Psychology
Neuroscience
Photic Stimulation
medicine.drug
Subjects
Details
- ISSN :
- 00283932
- Volume :
- 45
- Issue :
- 13
- Database :
- OpenAIRE
- Journal :
- Neuropsychologia
- Accession number :
- edsair.doi.dedup.....9fc037567a5a7af8a9b8ed1b473ec16b