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P19.01 Is reduced dose craniospinal radiation safe in adult medulloblastoma?

Authors :
D. Frappaz
M. Sunyach
E. Le Rhun
F. Laigle Donadey
A. Bonneville Levard
M. Massimino
Source :
Neuro-Oncology. 18:iv79-iv79
Publication Year :
2016
Publisher :
Oxford University Press (OUP), 2016.

Abstract

Medulloblastomas is an orphan disease in adults. Standard treatment of completely removed localised adult medulloblastoma includes a craniospinal, irradiation with 36 Gy to axis and 54 Gy to whole posterior fossa. Pediatric randomized study demonstrated that a decreased dose of 24 Gy to axis with 54 Gy limited to tumoral bed gives similar result as standard therapy, provided chemotherapy is associated. May this pediatric experience be extended to adult population?

Details

ISSN :
15235866 and 15228517
Volume :
18
Database :
OpenAIRE
Journal :
Neuro-Oncology
Accession number :
edsair.doi.dedup.....9f901c59bb271e1a1c45eee15b67c1b8
Full Text :
https://doi.org/10.1093/neuonc/now188.284