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Cryptococcal meningitis: A neglected NTD?
- Source :
- PLoS Neglected Tropical Diseases, Vol 11, Iss 6, p e0005575 (2017), PLoS Neglected Tropical Diseases, PLoS Neglected Tropical Diseases, Public Library of Science, 2017, 11 (6), pp.e0005575. ⟨10.1371/journal.pntd.0005575⟩, PLoS Neglected Tropical Diseases, 2017, 11 (6), pp.e0005575. ⟨10.1371/journal.pntd.0005575⟩, Molloy, S F, Chiller, T, Greene, G S, Burry, J, Govender, N P, Kanyama, C, Mfinanga, S, Lesikari, S, Mapoure, Y N, Kouanfack, C, Sini, V, Temfack, E, Boulware, D R, Dromer, F, Denning, D W, Day, J N, Stone, N R H, Bicanic, T, Jarvis, J N, Lortholary, O, Harrison, T S, Jaffar, S & Loyse, A 2017, ' Cryptococcal meningitis : A neglected NTD? ', PL o S Neglected Tropical Diseases, vol. 11, no. 6, e0005575 . https://doi.org/10.1371/journal.pntd.0005575
- Publication Year :
- 2017
- Publisher :
- Public Library of Science (PLoS), 2017.
-
Abstract
- International audience; Although HIV/AIDS has been anything but neglected over the last decade, opportunistic infections (OIs) are increasingly overlooked as large-scale donors shift their focus from acute care to prevention and earlier antiretroviral treatment (ART) initiation. Of these OIs, cryptococcal meningitis, a deadly invasive fungal infection, continues to affect hundreds of thousands of HIV patients with advanced disease each year and is responsible for an estimated 15%–20% of all AIDS-related deaths [1, 2]. Yet cryptococcal meningitis ranks amongst the most poorly funded “neglected” diseases in the world, receiving 0.2% of available relevant research and development (R&D) funding, according to Policy Cures’ 2016 Global Funding of Innovation for Neglected Diseases (G-Finder) Report [3, 4].
- Subjects :
- 0301 basic medicine
RNA viruses
Antifungal Agents
Biomedical Research
[SDV]Life Sciences [q-bio]
wc_503
Drug research and development
Meningitis, Cryptococcal
Global Health
Pathology and Laboratory Medicine
Pharmacology, Toxicology and Pharmaceutics(all)
Immunodeficiency Viruses
Infectious Diseases of the Nervous System
[SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases
Medicine and Health Sciences
Amphotericin
Neglected tropical diseases
wa_30
Death rates
Antimicrobials
Mortality rate
lcsh:Public aspects of medicine
Neglected Diseases
Drugs
3. Good health
Viewpoints
Infectious Diseases
Neurology
Medical Microbiology
Viral Pathogens
Viruses
Pathogens
Cryptococcal meningitis
medicine.medical_specialty
lcsh:Arctic medicine. Tropical medicine
lcsh:RC955-962
030106 microbiology
wc_503_5
Mycology
Microbiology
wc_245
03 medical and health sciences
Tropical Medicine
Microbial Control
Retroviruses
medicine
Humans
Intensive care medicine
Microbial Pathogens
Demography
Pharmacology
Antifungals
business.industry
Lentivirus
Public Health, Environmental and Occupational Health
Organisms
Biology and Life Sciences
HIV
lcsh:RA1-1270
Tropical Diseases
Health Care
Low and middle income countries
Immunology
People and Places
Health Statistics
Morbidity
business
Subjects
Details
- Language :
- English
- ISSN :
- 19352735 and 19352727
- Volume :
- 11
- Issue :
- 6
- Database :
- OpenAIRE
- Journal :
- PLoS Neglected Tropical Diseases
- Accession number :
- edsair.doi.dedup.....9f798dd9b9911d132d6f564b53e3cd1d