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Transcriptomic responses of the clam Meretrix meretrix to the organophosphorus pesticide (dimethoate)
- Source :
- Ecotoxicology. 28:539-549
- Publication Year :
- 2019
- Publisher :
- Springer Science and Business Media LLC, 2019.
-
Abstract
- Organophosphorus pesticides (OPs) play a certain role in promoting the development of agriculture and forestry, but they may cause potential harm to aquatic life when entering rivers and polluting water sources. Previous researches have shown that OPs participate in the regulation mechanism of aquatic organisms. Here, our aim is to determine the underlying mechanisms of one OP (dimethoate) at the transcriptional level using the clam Meretrix meretrix. 4119 DEGs were obtained from high-throughput RNA sequencing data. Then, expression profiles of some genes were verified by qPCR, which showed a positive correlation with the RNA sequencing results. 14,481 simple sequence repeats were also identified and could be further used as molecular markers. In addition, some oxidative, immune, and stress-related genes were further discussed and could also be used as biomarkers to indicate the biological response of dimethoate. This study will help to better understand the clam's response mechanism to dimethoate stress.
- Subjects :
- 0106 biological sciences
Insecticides
Health, Toxicology and Mutagenesis
010501 environmental sciences
Management, Monitoring, Policy and Law
Biology
Toxicology
01 natural sciences
Transcriptome
chemistry.chemical_compound
Gene expression
Animals
Ecotoxicology
Dimethoate
Gene
0105 earth and related environmental sciences
Genetics
RNA
General Medicine
Meretrix meretrix
Bivalvia
010602 entomology
chemistry
Organophosphorus pesticides
Water Pollutants, Chemical
Microsatellite Repeats
Subjects
Details
- ISSN :
- 15733017 and 09639292
- Volume :
- 28
- Database :
- OpenAIRE
- Journal :
- Ecotoxicology
- Accession number :
- edsair.doi.dedup.....9f44e3ceb0c0ad7952b8f0dcb5ae1ffb