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Tuning the Solid- and Solution-State Fluorescence of the Iron-Chelator Deferasirox
- Source :
- Journal of the American Chemical Society. 144:7382-7390
- Publication Year :
- 2022
- Publisher :
- American Chemical Society (ACS), 2022.
-
Abstract
- Deferasirox, an FDA-approved iron chelator, has gained increasing attention for use in anticancer and antimicrobial applications. Recent efforts by our group led to the identification of this core as an easy-to-visualize aggregation-induced emission platform, or AIEgen, that provides a therapeutic effect equivalent to deferasirox (
Details
- ISSN :
- 15205126 and 00027863
- Volume :
- 144
- Database :
- OpenAIRE
- Journal :
- Journal of the American Chemical Society
- Accession number :
- edsair.doi.dedup.....9f1eebd4c89678d4eabd3ab9ace40510