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Additional value of systolic wall thickening in myocardial stunning evaluated by stress-rest gated perfusion SPECT
- Source :
- Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology. 26(3)
- Publication Year :
- 2017
-
Abstract
- The aim of the present study is to evaluate the additional value of systolic wall thickening to myocardial perfusion in diagnosing myocardial stunning in patients with angiography proven coronary artery disease. We selected 91 ischemic patients (82 males; mean age 59.7 ± 10.3) with CAD documented by angiography. Ischemia was defined as a summed difference score ≥5. All patients underwent a 2-day gated perfusion SPECT protocol. The patients received a dose of 740 MBq of 99mTc-tetrofosmin after stress and at rest. Treadmill maximal exercise tests were performed on all patients. The post-stress LVEF was significantly lower than rest LVEF (48.1% ± 10.3% vs 50.3% ± 10.7%; P = .0001). The wall thickening summed difference score was 4.44 ± 4.13 (P = .0001). At a multivariate regression analysis, only WT-SDS as independent variable was significantly correlated with myocardial ischemia (SDS). We also divided patients according to SDS in those with mild (SDS
- Subjects :
- Male
medicine.medical_specialty
Ischemia
Coronary Artery Disease
030204 cardiovascular system & hematology
030218 nuclear medicine & medical imaging
Coronary artery disease
03 medical and health sciences
0302 clinical medicine
Predictive Value of Tests
Internal medicine
Coronary Circulation
Medicine
Humans
Radiology, Nuclear Medicine and imaging
cardiovascular diseases
Aged
Myocardial Stunning
Tomography, Emission-Computed, Single-Photon
Myocardial stunning
Ejection fraction
medicine.diagnostic_test
business.industry
Stunning
Gated Blood-Pool Imaging
Stroke Volume
Middle Aged
medicine.disease
medicine.anatomical_structure
Ventricle
Angiography
Cardiology
Exercise Test
Female
Cardiology and Cardiovascular Medicine
business
Perfusion
Subjects
Details
- ISSN :
- 15326551
- Volume :
- 26
- Issue :
- 3
- Database :
- OpenAIRE
- Journal :
- Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology
- Accession number :
- edsair.doi.dedup.....9f184e5998792c97cba18c96fab0c25c