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Connexins in the heart
- Source :
- Cell and tissue research. 360(3)
- Publication Year :
- 2014
-
Abstract
- Connexins are essential in the propagation of electrical activity throughout the heart and are an important determinant of conduction velocity. Their dysfunction is an important factor in the genesis of abnormal cardiac rhythm and is relevant to the pathogenesis of a wide variety of cardiac pathologies. Here, we review the basic biology of connexins in the heart but particularly focus on their abnormal function in cardiac disease.
- Subjects :
- medicine.medical_specialty
Histology
Antiarrhythmic peptide
Cardiac pathology
Disease
Biology
Connexins
Pathology and Forensic Medicine
Pathogenesis
Internal medicine
medicine
Chronic atrial fibrillation
Animals
Humans
Molecular Targeted Therapy
Cardiac conduction abnormalities
Myocardium
Myocardium metabolism
Gap Junctions
Arrhythmias, Cardiac
Cell Biology
medicine.anatomical_structure
cardiovascular system
Cardiology
Intercalated disc
Neuroscience
Subjects
Details
- ISSN :
- 14320878
- Volume :
- 360
- Issue :
- 3
- Database :
- OpenAIRE
- Journal :
- Cell and tissue research
- Accession number :
- edsair.doi.dedup.....9eee0dda3aaad190a39d0de0598a4ba4