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One-day postoperative intraocular pressure spikes after phacoemulsification cataract surgery in patients taking tamsulosin
- Source :
- Journal of cataract and refractive surgery. 42(12)
- Publication Year :
- 2016
-
Abstract
- Purpose To evaluate the relationship between 1-day postoperative intraocular pressure (IOP) after phacoemulsification cataract surgery and tamsulosin use. Setting University of Colorado Health Eye Center, Aurora, Colorado, USA. Design Retrospective cohort study. Methods Registry data from men who had cataract surgery were used. Patients taking tamsulosin at the time of surgery were included as cases, while patients with no history of tamsulosin use were used as controls. The primary outcome was a 1-day postoperative IOP spike defined as an IOP increase greater than 10 mm Hg compared with baseline or a 1-day postoperative IOP of 30 mm Hg or higher. General estimating equations were used for analysis. Results The study comprised 584 men (864 eyes). An IOP increase greater than 10 mm Hg or IOP 30 mm Hg or higher after cataract surgery occurred in 12.4% and 9.3%, respectively, of eyes in the tamsulosin group versus 4.4% and 2.1%, respectively, in the control group (all P = .001). After adjusting for significant covariates, patients on tamsulosin were 2.6 times (95% confidence interval [CI], 1.2-5.7; P = .01] and 3.8 (95% CI, 1.3-10.9; P = .01) more likely to have a 1-day postoperative IOP increase greater than 10 mm Hg or a 1-day postoperative IOP of 30 mm Hg or higher. Conclusion Patients on tamsulosin had an increased risk of a 1-day postoperative IOP spike after cataract surgery, showing the importance of identifying patients on tamsulosin preoperatively to better manage and potentially mitigate IOP spikes. Financial Disclosure None of the authors has a financial or proprietary interest in any material or method mentioned.
- Subjects :
- Male
Tamsulosin
Intraocular pressure
medicine.medical_specialty
genetic structures
medicine.medical_treatment
Cataract Extraction
Cataract
03 medical and health sciences
0302 clinical medicine
Lens Implantation, Intraocular
Ophthalmology
Medicine
Humans
In patient
Intraocular Pressure
Retrospective Studies
Sulfonamides
Phacoemulsification
business.industry
Retrospective cohort study
Cataract surgery
eye diseases
Sensory Systems
Confidence interval
Increased risk
Anesthesia
030221 ophthalmology & optometry
Adrenergic alpha-1 Receptor Antagonists
Surgery
sense organs
business
030217 neurology & neurosurgery
medicine.drug
Subjects
Details
- ISSN :
- 18734502
- Volume :
- 42
- Issue :
- 12
- Database :
- OpenAIRE
- Journal :
- Journal of cataract and refractive surgery
- Accession number :
- edsair.doi.dedup.....9ee5a6d2e0a565510e116fb0e8fd3904