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Systemic lupus erythematosus is associated with poor outcome after acute myocardial infarction
- Source :
- Nutrition, Metabolism and Cardiovascular Diseases. 29:1400-1407
- Publication Year :
- 2019
- Publisher :
- Elsevier BV, 2019.
-
Abstract
- Background Systemic lupus erythematosus (SLE) is associated with a higher risk of cardiovascular disease. However, it is not clear whether or not SLE is associated with poor outcomes after acute myocardial infarction (AMI). Methods and results Using the Taiwan National Health Insurance Database, we identified the SLE group as patients with AMI who have a concurrent discharge diagnosis of SLE. We also selected an age-, sex-, hospital level-, and admission calendar year-matched non-SLE group at a ratio of 1:3 from the total non-SLE group. One hundred fifty-one patients with SLE, 113,791 patients without SLE, and 453 matched patients without SLE were admitted with a diagnosis of AMI. Patients with SLE were significantly younger, predominantly female, and more likely to have chronic kidney disease than those without SLE. The in-hospital mortality rates were 12.6%, 9.0%, and 4.2% in the SLE, total non-SLE, and matched non-SLE groups, respectively. The in-hospital mortality was significantly higher in the SLE group than in the total non-SLE group (OR = 1.98; 95% CI = 1.2–3.26) and the matched non-SLE group (mortality OR = 2.20; 95% CI = 1.06–4.58). In addition, the SLE group was associated with a borderline significant risk of prolonged hospitalization when compared with the non-SLE group. Conclusion SLE is associated with a higher risk of in-hospital mortality and a borderline significantly higher risk of prolonged hospitalization after AMI.
- Subjects :
- Adult
Male
medicine.medical_specialty
Time Factors
Databases, Factual
Endocrinology, Diabetes and Metabolism
Myocardial Infarction
Taiwan
Medicine (miscellaneous)
030209 endocrinology & metabolism
Disease
030204 cardiovascular system & hematology
Risk Assessment
Young Adult
03 medical and health sciences
Sex Factors
0302 clinical medicine
Risk Factors
immune system diseases
Internal medicine
medicine
Humans
Lupus Erythematosus, Systemic
Hospital Mortality
Myocardial infarction
Significant risk
Renal Insufficiency, Chronic
skin and connective tissue diseases
Aged
Discharge diagnosis
Nutrition and Dietetics
business.industry
Mortality rate
Age Factors
Hospital level
Length of Stay
Middle Aged
Prognosis
medicine.disease
National health insurance
Female
Cardiology and Cardiovascular Medicine
business
Kidney disease
Subjects
Details
- ISSN :
- 09394753
- Volume :
- 29
- Database :
- OpenAIRE
- Journal :
- Nutrition, Metabolism and Cardiovascular Diseases
- Accession number :
- edsair.doi.dedup.....9ecd531357a7e63953dcdd3b93f534f4