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Tenosynovial giant cell tumor involving the cervical spine: A case report
- Source :
- World Journal of Clinical Cases
- Publication Year :
- 2021
- Publisher :
- Baishideng Publishing Group Inc, 2021.
-
Abstract
- Background Tenosynovial giant cell tumors (TGCTs) are a frequent benign proliferative disease originating from the synovial membrane. However, TGCTs rarely occur in the spine. The purpose of this paper is to report a case of TGCT occurring in the cervical spine. Although the disease is rare, it is essential to consider the possibility of TGCT in axial skeletal lesions. Awareness of spinal TGCTs is important because their characteristics are similar to common spinal tumor lesions. Case summary A 49-year-old man with a 2-year history of neck pain and weakness in both lower extremities was referred to our ward. Imaging revealed a mass extending from the left epidural space to the C4-5 paravertebral muscles with uneven enhancement. The tumor originated in the synovium of the C4-5 lesser joint and eroded mainly the C4-5 vertebral arch and spine. Puncture biopsy was suggestive of a giant cell-rich lesion. The patient had pulmonary tuberculosis, and we first administered anti-tuberculosis treatment. After the preoperative requirements of the anti-tuberculosis treatment were met, we used a posterior cervical approach to completely remove the mass after fixation with eight pedicle screws. The mass was identified as a TGCT by postoperative immunohistochemical analysis. Recurrence was not detected after 1 year of follow-up. Conclusion Spinal TGCTs are often misdiagnosed. The radiological changes are not specific. The ideal treatment comprises complete excision with proper internal fixation, which can significantly reduce postoperative recurrence.
- Subjects :
- medicine.medical_specialty
medicine.medical_treatment
Cervical vertebrae
Tenosynovial giant cell tumors
Lesion
03 medical and health sciences
0302 clinical medicine
Case report
medicine
Internal fixation
Giant Cell Tumors
Fixation (histology)
Neck pain
Tumor
business.industry
General Medicine
Epidural space
Spine
medicine.anatomical_structure
030220 oncology & carcinogenesis
030211 gastroenterology & hepatology
Radiology
Synovial membrane
medicine.symptom
business
Spinal diseases
Subjects
Details
- Language :
- English
- ISSN :
- 23078960
- Volume :
- 9
- Issue :
- 14
- Database :
- OpenAIRE
- Journal :
- World Journal of Clinical Cases
- Accession number :
- edsair.doi.dedup.....9ebfaac6a3a74f8374db9b9f905ba698