Design Of A Multichannel Asic For Large Scale Spatio-temporal Distributed Stimulation Of Neural Tissue

We present an ASIC designed for electrical stimulation of neural tissue using multielectrode arrays. The ASIC is foreseen for applications in systems requiring simultaneous stimulation and recording of signals from various types of neural tissue, both in-vitro and in-vivo. The developed STIM64 ASIC includes 64 independent stimulation channels, which are capable to generate arbitrarily defined bipolar current or voltage waveforms, controlled in real time with time resolution of 50 mus and amplitude resolution of 7 bits. The amplitude range of output signal can be scaled over a very wide range, what ensures compatibility with various electrode arrays of different size and geometry. Each channel is equipped with a real-time controlled stimulation artifact suppressor, which reduces the 'dead time' between the stimulation pulse and system being ready for signal recording