Back to Search
Start Over
Single-dose intra-articular bupivacaine plus morphine after knee arthroscopic surgery: a meta-analysis of randomised placebo-controlled studies
- Source :
- BMJ Open
- Publication Year :
- 2015
- Publisher :
- BMJ, 2015.
-
Abstract
- Objectives To evaluate the efficacy and safety of single-dose intra-articular bupivacaine plus morphine after knee arthroscopic surgery. Design Meta-analysis. Data sources and study eligibility criteria A comprehensive literature search, using Medline (1966–2014), the Cochrane Central Register of Controlled Trials and Embase databases, was conducted to identify randomised placebo-controlled trials that used a combination of single-dose intra-articular bupivacaine and morphine for postoperative pain relief. Results 12 articles were included in this meta-analysis. The mean visual analogue scale (VAS) scores of the bupivacaine plus morphine group were significantly lower than those of the placebo group (weighted mean difference (WMD) −1.75; 95% CI −2.16 to −1.33; p
- Subjects :
- medicine.medical_specialty
Knee Joint
Visual analogue scale
medicine.medical_treatment
ANAESTHETICS
Placebo
STATISTICS & RESEARCH METHODS
Arthroscopy
Musculoskeletal Pain
medicine
Humans
Knee
Anesthetics, Local
Saline
Bupivacaine
Pain, Postoperative
Morphine
medicine.diagnostic_test
business.industry
Research
General Medicine
Surgery
Analgesics, Opioid
Treatment Outcome
Evidence Based Practice
Anesthesia
Meta-analysis
Analgesia
business
medicine.drug
Subjects
Details
- ISSN :
- 20446055
- Volume :
- 5
- Database :
- OpenAIRE
- Journal :
- BMJ Open
- Accession number :
- edsair.doi.dedup.....9e840c076efc525cd52cc48cd73ec840