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New Type III CRISPR variant and programmable RNA targeting tool: Oh, thank heaven for Cas7-11
- Source :
- Mol Cell
- Publication Year :
- 2021
-
Abstract
- Ozcan et al. (2021) and van Beljouw et al. (2021) characterize a novel Type III-E CRISPR-Cas subtype, composed of a single polypeptide with crRNA processing and sequence-specific RNA cleavage activities, that provides a new RNA knockdown tool for mammalian cells with fewer off-target effects than current technologies.
Details
- Language :
- English
- Database :
- OpenAIRE
- Journal :
- Mol Cell
- Accession number :
- edsair.doi.dedup.....9e081b3ce4ff21e84d90e60fd65854c7