Contribution of a heparin-binding haemagglutinin interferon-gamma release assay to the detection of Mycobacterium tuberculosis infection in HIV-infected patients: comparison with the tuberculin skin test and the QuantiFERON®-TB Gold In-tube

Authors :: Kinda Schepers
Fanny Domont
Myriam Libin
Chloe Wyndham-Thomas
Violette Dirix
Marc Loyens
Camille Locht
Jean-Christophe Goffard
Marc Hildebrand
Charlotte Martin
Jean-Paul Van Vooren
Françoise Mascart
Source :: BMC Infectious Diseases, BMC infectious diseases, 15
Publication Year :: 2015
Publisher :: BioMed Central, 2015.
Abstract: The screening and treatment of latent tuberculosis (TB) infection reduces the risk of progression to active disease and is currently recommended for HIV-infected patients. The aim of this study is to evaluate, in a low TB incidence setting, the potential contribution of an interferon-gamma release assay in response to the mycobacterial latency antigen Heparin-Binding Haemagglutinin (HBHA-IGRA), to the detection of Mycobacterium tuberculosis infection in HIV-infected patients.<br />SCOPUS: ar.j<br />info:eu-repo/semantics/published

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