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High-Dose-Rate Intracavitary Brachytherapy Under Conscious Sedation a Viable Practical Alternative to Spinal Anaesthesia in Carcinoma Cervix: A Retrospective Study in a Tertiary Care Centre in Eastern India

Authors :
Avinash Badajena
Minakshi Mishra
Adhar Amritt
Dillip Kumar Parida
Ashutosh Pattanaik
Anupam Muraleedharan
Bikash Ranjan Mahapatra
Satyabrata Kanungo
Bijay Kumar Barik
Sandip Kumar Barik
Saroj Kumar Das Majumdar
Sovan Sarang Dhar
Source :
Cureus
Publication Year :
2021
Publisher :
Cureus, Inc., 2021.

Abstract

Introduction Intracavitary brachytherapy (ICBT) is an integral component in the management of locally advanced cervical cancer. Spinal anaesthesia is the preferred mode of pain management during brachytherapy procedures. In high volume, resource constraint settings, it is difficult to provide spinal anaesthesia to all patients. This study attempts dosimetric comparison of high-dose-rate ICBT with spinal anaesthesia to that under conscious sedation to find out whether brachytherapy under conscious sedation is comparable with spinal anaesthesia. Methods Retrospective data of total of 56 cervical cancer patients who received ICBT after completion of external beam radiotherapy (EBRT) were collected. Among these 56 patients, 28 patients received brachytherapy under spinal anaesthesia (SA group) and the rest under conscious sedation (CS group). Brachytherapy dose was 7 Gray per fraction weekly for three weeks. Thus, 84 brachytherapy plans of each group were analysed with respect to doses received by points A, B, P and Organs at Risk. Results The mean doses received by points A, B and P were comparable in SA and CS groups (p-value >0.05). Similarly, the mean doses received by Organs at Risk (rectum, urinary bladder, and sigmoid colon) were also comparable in both the groups (p-value>0.05). Conclusion ICBT under CS is dosimetrically non-inferior to SA, which makes it an alternative option.

Details

ISSN :
21688184
Database :
OpenAIRE
Journal :
Cureus
Accession number :
edsair.doi.dedup.....9d7ef7b254d57429b100b5d813e00283
Full Text :
https://doi.org/10.7759/cureus.20063