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Nutrient-based dietary patterns and the risk of head and neck cancer: a pooled analysis in the International Head and Neck Cancer Epidemiology consortium
- Source :
- Annals of Oncology, Annals of Oncology, Elsevier, 2012, 23 (7), pp.1869-80. ⟨10.1093/annonc/mdr548⟩
- Publication Year :
- 2011
-
Abstract
- Edefonti, V Hashibe, M Ambrogi, F Parpinel, M Bravi, F Talamini, R Levi, F Yu, G Morgenstern, H Kelsey, K McClean, M Schantz, S Zhang, Z Chuang, S Boffetta, P La Vecchia, C Decarli, A eng CA100679/CA/NCI NIH HHS/ CA78609/CA/NCI NIH HHS/ P50CA90388/CA/NCI NIH HHS/ R01CA51845/CA/NCI NIH HHS/ R01DA11386/DA/NIDA NIH HHS/ R03CA113157/CA/NCI NIH HHS/ R03CA77954/CA/NCI NIH HHS/ R21ES011667/ES/NIEHS NIH HHS/ T32CA09142/CA/NCI NIH HHS/ U01CA96134/CA/NCI NIH HHS/ Meta-Analysis Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't England 2011/11/30 06:00 Ann Oncol. 2012 Jul;23(7):1869-80. doi: 10.1093/annonc/mdr548. Epub 2011 Nov 28.; International audience; BACKGROUND: The association between dietary patterns and head and neck cancer has rarely been addressed. PATIENTS AND METHODS: We used individual-level pooled data from five case-control studies (2452 cases and 5013 controls) participating in the International Head and Neck Cancer Epidemiology consortium. A posteriori dietary patterns were identified through a principal component factor analysis carried out on 24 nutrients derived from study-specific food-frequency questionnaires. Odds ratios (ORs) and corresponding 95% confidence intervals (CIs) were estimated using unconditional logistic regression models on quintiles of factor scores. RESULTS: We identified three major dietary patterns named 'animal products and cereals', 'antioxidant vitamins and fiber', and 'fats'. The 'antioxidant vitamins and fiber' pattern was inversely related to oral and pharyngeal cancer (OR=0.57, 95% CI 0.43-0.76 for the highest versus the lowest score quintile). The 'animal products and cereals' pattern was positively associated with laryngeal cancer (OR=1.54, 95% CI 1.12-2.11), whereas the 'fats' pattern was inversely associated with oral and pharyngeal cancer (OR=0.78, 95% CI 0.63-0.97) and positively associated with laryngeal cancer (OR=1.69, 95% CI 1.22-2.34). CONCLUSIONS: These findings suggest that diets rich in animal products, cereals, and fats are positively related to laryngeal cancer, and those rich in fruit and vegetables inversely related to oral and pharyngeal cancer.
- Subjects :
- medicine.medical_specialty
INHANCE
pattern
Logistic regression
Risk Factors
Internal medicine
Epidemiology
International Head and Neck Cancer Epidemiology Consortium
medicine
Odds Ratio
Nutrient-based
cancer
Humans
pooled analysi
Dietary patterns
Head and neck cancer
Laryngeal Neoplasms
risk
Diet, Dietary patterns, Factor analysis, Head and neck cancer, INHANCE, Nutrients
Mouth neoplasm
business.industry
Case-control study
Cancer
Pharyngeal Neoplasms
Hematology
Odds ratio
Nutrients
Feeding Behavior
Original Articles
head
medicine.disease
neck
Confidence interval
Surgery
Diet
Case-Control Studies Diet/*adverse effects *Food Habits Humans Laryngeal Neoplasms/*etiology Mouth Neoplasms/*etiology Odds Ratio Pharyngeal Neoplasms/*etiology Risk Factors
Oncology
Case-Control Studies
dietary
[SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie
Mouth Neoplasms
Factor analysis
business
Subjects
Details
- ISSN :
- 15698041 and 09237534
- Volume :
- 23
- Issue :
- 7
- Database :
- OpenAIRE
- Journal :
- Annals of oncology : official journal of the European Society for Medical Oncology
- Accession number :
- edsair.doi.dedup.....9d78cc06559e8e3464b3942ab63b86b8