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Bacteremia Due to Campylobacter Species: Clinical Findings and Antimicrobial Susceptibility Patterns
Bacteremia Due to Campylobacter Species: Clinical Findings and Antimicrobial Susceptibility Patterns
- Source :
- Scopus-Elsevier
- Publication Year :
- 1997
- Publisher :
- Oxford University Press (OUP), 1997.
-
Abstract
- From 1979 to 1996, 58 patients (mean age, 39.4 years) were treated for bacteremia due to Campylobacter species at the Hospitals Vall d'Hebron in Barcelona, Spain. Bacteremia was considered to be hospital acquired in 30% of these patients. Almost all the patients (93%) had underlying conditions; liver cirrhosis was the most frequent (34% of patients), and neoplasia, immunosuppressive therapy, and human immunodeficiency virus disease were also common. Of the 58 Campylobacter strains isolated, 81% were C. jejuni, 10% were Campylobacter species, 7% were C. fetus, and one (2%) was C. coli. Resistance rates were: cephalothin, 82%; co-trimoxazole, 79%; quinolones, 54%; ampicillin, 20%; amoxicillin/clavulanate, 4%; erythromycin, 7%; gentamicin, 0; and tetracyclines, 0. Even though the majority of patients were immunocompromised, mortality was low (10.5%), and only one patient relapsed. Because of the high level of resistance to the quinolones in Campylobacter species, these drugs should not be used as empirical treatment, at least in Spain. Although the macrolides remain the antibiotics of choice, amoxicillin/clavulanate may be an effective alternative therapy.
- Subjects :
- Adult
Male
Microbiology (medical)
medicine.medical_specialty
Adolescent
medicine.drug_class
Antibiotics
Erythromycin
Bacteremia
Microbial Sensitivity Tests
medicine.disease_cause
Gastroenterology
Microbiology
Internal medicine
Ampicillin
Campylobacter Infections
Humans
Medicine
Child
Aged
Retrospective Studies
Aged, 80 and over
Cross Infection
business.industry
Campylobacter
Infant, Newborn
Infant
Middle Aged
Amoxicillin
medicine.disease
Infectious Diseases
Child, Preschool
Female
Gentamicin
Amoxicillin-Potassium Clavulanate Combination
business
medicine.drug
Subjects
Details
- ISSN :
- 15376591 and 10584838
- Volume :
- 25
- Database :
- OpenAIRE
- Journal :
- Clinical Infectious Diseases
- Accession number :
- edsair.doi.dedup.....9d7406727d8df5571c8e532542a7ddeb
- Full Text :
- https://doi.org/10.1086/516127