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Drug-class-specific changes in the volume and cost of antidiabetic medications in Poland between 2012 and 2015
- Source :
- PLoS ONE, PLoS ONE, Vol 12, Iss 6, p e0178764 (2017)
- Publication Year :
- 2017
- Publisher :
- Public Library of Science (PLoS), 2017.
-
Abstract
- Aim to investigate the drug-class-specific changes in the volume and cost of antidiabetic medications in Poland in 2012–2015. Methods This retrospective analysis was conducted based on the National Health Fund database covering an entire Polish population. The volume of antidiabetic medications is reported according to ATC/DDD methodology, costs—in current international dollars, based on purchasing power parity. Results During a 4-year observational period the number of patients, consumption of antidiabetic drugs and costs increased by 17%, 21% and 20%, respectively. Biguanides are the basic diabetes medication with a 39% market share. The insulin market is still dominated by human insulins, new antidiabetics (incretins, thiazolidinediones) are practically absent. Insulins had the largest share in diabetes medications expenditures (67% in 2015). The increase in antidiabetic medications costs over the analysed period of time was mainly caused by the increased use of insulin analogues. Conclusions The observed tendencies correspond to the evidence-based HTA recommendations. The reimbursement status, the ratio of cost to clinical outcomes and data on the long-term safety have a deciding impact on how a drug is used.
- Subjects :
- medicine.medical_treatment
Biguanides
lcsh:Medicine
Biochemistry
Geographical Locations
Endocrinology
0302 clinical medicine
Medicine and Health Sciences
Insulin
Public and Occupational Health
030212 general & internal medicine
Market share
lcsh:Science
health care economics and organizations
Reimbursement
media_common
Multidisciplinary
Traditional medicine
Pharmaceutics
Drug Information
Drugs
Drug Marketing
Europe
Drug class
Research Article
Drug
medicine.medical_specialty
Drug Research and Development
Drug Administration
Endocrine Disorders
media_common.quotation_subject
030209 endocrinology & metabolism
Incretins
Reimbursement Mechanisms
03 medical and health sciences
Drug Therapy
Diabetes mellitus
Diabetes Mellitus
medicine
Humans
Hypoglycemic Agents
Retrospective Studies
Diabetic Endocrinology
Pharmacology
Insurance, Health
Health Care Policy
Health economics
business.industry
lcsh:R
Biology and Life Sciences
Retrospective cohort study
Drug Policy
medicine.disease
Hormones
Health Care
Diabetes Mellitus, Type 2
Metabolic Disorders
People and Places
Emergency medicine
lcsh:Q
Thiazolidinediones
Poland
Health Expenditures
business
Subjects
Details
- ISSN :
- 19326203
- Volume :
- 12
- Database :
- OpenAIRE
- Journal :
- PLOS ONE
- Accession number :
- edsair.doi.dedup.....9d6dfb720c02ca881448ccf2626d7e0e