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Impact of diabetes on mortality and complications after coronary artery by-pass graft operation in patients with left main coronary artery disease

Authors :
Hanna Bachórzewska-Gajewska
Tomasz Hirnle
Jolanta Malyszko
Konrad Nowak
Sławomir Dobrzycki
Anna Tomaszuk-Kazberuk
Małgorzata Zalewska-Adamiec
Source :
Advances in medical sciences. 59(2)
Publication Year :
2013

Abstract

Left main disease (LMD) is a severe form of coronary artery disease (CAD). Fifty percent of patients with LMD treated conservatively die within 3-5 years of diagnosis. The aim of the study was to assess the influence of type 2 diabetes on early and late (2-year) prognosis and the risk of complications after coronary artery by-pass graft (CABG) surgery in patients with LMD.We enrolled 257 patients diagnosed with LMD. 169 (67%) underwent CABG, 19 (8%) percutaneous coronary intervention (PCI) without left main stem protection. 30 (12%) patients had CABG previously. Patients treated with CABG were divided into two groups - with and without diabetes. There were 43 (25.4%) patients with diabetes and 126 (74.6%) without diabetes.We observed more complications with wound healing (40.5% vs. 12.8%, p0.001) and sternal dehiscence (23.8% vs. 4.0%, p0.001) after CABG in patients with diabetes. There were no differences in 7-day, 30-day, 3-month and 1-year mortality. 2-Year mortality was also similar in both groups (11.6% vs. 11.1%, p=0.928). Patients with diabetes were more frequently hospitalized due to other reasons than angina (39.5% vs. 20.6%, p=0.014).Patients with diabetes and LMD had more often complications with wound healing and sternal dehiscence after CABG than patients without diabetes. Type 2 diabetes did not influence early and late mortality in patients with LMD treated with cardiac surgery, but the presence of diabetes was associated with more frequent hospitalizations.

Details

ISSN :
18984002
Volume :
59
Issue :
2
Database :
OpenAIRE
Journal :
Advances in medical sciences
Accession number :
edsair.doi.dedup.....9d41f048f8970f072889ad525e701774