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Ultrasound shear wave elastography of breast lesions: correlation of anisotropy with clinical and histopathological findings
- Source :
- Cancer Imaging, Cancer Imaging, Vol 18, Iss 1, Pp 1-11 (2018)
- Publication Year :
- 2017
-
Abstract
- Background Ultrasound shear-wave elastography (SWE) may increase specificity of breast lesion assessment with ultrasound, but elasticity measurements may change with transducer orientation, defined as anisotropy. In this study, we aimed to observe the anisotropy of SWE of breast lesions, and its correlation with clinical and histopathological findings. Methods This retrospective study was approved by institutional review board. From June 2014 to June 2015, a total of 276 women (mean age, 48.75 ± 12.12 years) with 276 breast lesions (174 malignant, 102 benign) were enrolled for conventional ultrasound and SWE before surgical excision. Elasticity modulus in the longest diameter and orthogonal diameter were recorded, including maximum elasticity (Emax), mean elasticity (Emean), standard deviation (Esd) and ratio between mean elasticity of lesion and normal fatty tissue (Eratio). Anisotropy coefficients including anisotropic difference (AD) and anisotropy factors (AF) were calculated, and correlations with malignancy, tumor size, palpability, movability, lesion location and histopathology were analyzed. Results The average Emax, Emean, Esd and Eratio of the longest diameter were significantly higher than orthogonal diameter (P
- Subjects :
- lcsh:Medical physics. Medical radiology. Nuclear medicine
Adult
medicine.medical_specialty
BI-RADS
lcsh:R895-920
Breast Neoplasms
Malignancy
lcsh:RC254-282
030218 nuclear medicine & medical imaging
Correlation
Lesion
03 medical and health sciences
0302 clinical medicine
Breast cancer
Breast lesion
Ultrasound
medicine
Humans
Radiology, Nuclear Medicine and imaging
Aged
Radiological and Ultrasound Technology
medicine.diagnostic_test
business.industry
Reproducibility of Results
General Medicine
Middle Aged
lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens
medicine.disease
Elasticity
Oncology
030220 oncology & carcinogenesis
Shear wave elastography
Anisotropy
Elasticity Imaging Techniques
Histopathology
Female
Elastography
Ultrasonography, Mammary
medicine.symptom
Nuclear medicine
business
Research Article
Subjects
Details
- ISSN :
- 14707330
- Volume :
- 18
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- Cancer imaging : the official publication of the International Cancer Imaging Society
- Accession number :
- edsair.doi.dedup.....9d0673bfe29ab2e724c939a5428c9c4e