Proteomic profiling reveals dysregulated mitochondrial complex subunits responsible for myocardial toxicity induced by SiNPs

Authors :: Xinying Zhao
Hailin Xu
Yan Li
Ru Ma
Yi Qi
Min Zhang
Caixia Guo
Zhiwei Sun
Yanbo Li
Source :: The Science of the total environment. 857(Pt 1)
Publication Year :: 2022
Abstract: The relationship between environmental exposure to silica nanoparticles (SiNPs) and adverse cardiac outcomes has received more attention. Our recent work has revealed a size-dependent impact of the intratracheal instilled SiNPs on cardiac health of ApoE

Subjects :: Proteomics
Environmental Engineering
Mice, Knockout, ApoE
Silicon Dioxide
Pollution
Cardiotoxicity
Mitochondria
Mice
Tandem Mass Spectrometry
Environmental Chemistry
Animals
Nanoparticles
Waste Management and Disposal
Chromatography, Liquid

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