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Tri-modality Cavitation Mapping in Shock Wave Lithotripsy
- Source :
- J Acoust Soc Am
- Publication Year :
- 2020
-
Abstract
- Shock wave lithotripsy (SWL) has been widely used for non-invasive treatment of kidney stones. Cavitation plays an important role in stone fragmentation, yet it may also contribute to renal injury during SWL. It is therefore crucial to determine the spatiotemporal distributions of cavitation activities to maximize stone fragmentation while minimizing tissue injury. Traditional cavitation detection methods include high-speed optical imaging, active cavitation mapping (ACM), and passive cavitation mapping (PCM). While each of the three methods provides unique information about the dynamics of the bubbles, PCM has most practical applications in biological tissues. To image the dynamics of cavitation bubble collapse, we previously developed a sliding-window PCM (SW-PCM) method to identify each bubble collapse with high temporal and spatial resolution. In this work, to further validate and optimize the SW-PCM method, we have developed tri-modality cavitation imaging that includes three-dimensional high-speed optical imaging, ACM, and PCM seamlessly integrated in a single system. Using the tri-modality system, we imaged and analyzed laser-induced single cavitation bubbles in both free field and constricted space and shock wave-induced cavitation clusters. Collectively, our results have demonstrated the high reliability and spatial-temporal accuracy of the SW-PCM approach, which paves the way for the future in vivo applications on large animals and humans in SWL.
- Subjects :
- Materials science
Acoustics and Ultrasonics
Acoustics
Bubble
FOS: Physical sciences
Shock wave lithotripsy
Applied Physics (physics.app-ph)
01 natural sciences
030218 nuclear medicine & medical imaging
03 medical and health sciences
Kidney Calculi
0302 clinical medicine
Optical imaging
Arts and Humanities (miscellaneous)
Renal injury
Lithotripsy
0103 physical sciences
Animals
Humans
010301 acoustics
Image resolution
Cavitation bubble
Biomedical Acoustics
Reproducibility of Results
Physics - Applied Physics
Physics - Medical Physics
Shock (mechanics)
Cavitation
Medical Physics (physics.med-ph)
Subjects
Details
- Language :
- English
- Database :
- OpenAIRE
- Journal :
- J Acoust Soc Am
- Accession number :
- edsair.doi.dedup.....9cc047c4f6eaf7dc1d4c82d4e5ed88b5