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A New Triterpenoid from Teucrium viscidum

Authors :
Jinwen Zhang
Yanyan Si
Guangmin Yao
Zengwei Luo
Xincai Hao
Yonghui Zhang
Guangxin Xia
Yongbo Xue
Source :
Molecules; Volume 18; Issue 1; Pages: 1262-1269, Molecules, Vol 18, Iss 1, Pp 1262-1269 (2013), Molecules
Publication Year :
2013
Publisher :
MDPI AG, 2013.

Abstract

A new ursane-type triterpenoid, 3β-hydroxy-urs-30-p-Z-hydroxycinnamoyloxy-12-en-28-oic-acid (1), together with three known triterpenoids, 3β-hydroxy-urs-30-p-E-hydroxycinnamoyloxy-12-en-28-oic-acid (2), 2α,3β,19α-trihydroxy-urs-12-en-28-oic-acid (3), and ursolic acid (4), four known lignans, pinoresinol (5), 9α-hydroxypinoresinol (6), (+)-medioresinol (7), and (+)-kobusin (8), and two steroids, β-sitosterol (9), and daucosterol (10), were isolated from the whole parts of Teucrium viscidum. Their structures were established by a combination of spectroscopic data analysis, besides comparison with literature data. Compounds 1–4 were evaluated for their inhibitory activities against 11β-hydroxysteroid dehydrogenase 1 (11β-HSD1).

Details

ISSN :
14203049
Volume :
18
Database :
OpenAIRE
Journal :
Molecules
Accession number :
edsair.doi.dedup.....9c8c5e5e5d0935a9eb5c216204fc5bf7
Full Text :
https://doi.org/10.3390/molecules18011262