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Sesquiterpenes from the aerial part of Chloranthus japonicus and their cytotoxicities
- Source :
- Fitoterapia. 83(8)
- Publication Year :
- 2012
-
Abstract
- Four new sesquiterpenes, chlorajapolides F-I (1-4), along with nine known terpenoids (5-13) were isolated from the aerial part of Chloranthus japonicus. Their structures were elucidated on the basis of spectroscopic analysis, and a lindenane sesquiterpene, named 9-hydroxy-heterogorgiolide, previously isolated from the C. japonicus, was revised as its 8-epimer (1a). Moreover, methanol extract (ME), EtOAc fraction (EF), water fraction (WF), and all isolates (1a, 1-13) were evaluated for their cytotoxicities using two human cancer cell lines.
- Subjects :
- Pharmacology
Plant Components
Models, Molecular
Molecular Structure
Chloranthus japonicus
Stereochemistry
General Medicine
Plant Components, Aerial
Sesquiterpene
Antineoplastic Agents, Phytogenic
Terpenoid
chemistry.chemical_compound
Magnoliopsida
chemistry
Water fraction
Cell Line, Tumor
Drug Discovery
Humans
Sesquiterpenes
Human cancer
Subjects
Details
- ISSN :
- 18736971
- Volume :
- 83
- Issue :
- 8
- Database :
- OpenAIRE
- Journal :
- Fitoterapia
- Accession number :
- edsair.doi.dedup.....9c34662fa3280e5f2f41f6720a8fa5cd