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Outcomes of donation after circulatory death kidneys undergoing hypothermic machine perfusion following static cold storage: A UK population-based cohort study

Authors :
James Hodson
Kamlesh Patel
Andrew R. Ready
Jay Nath
Nicholas Inston
Source :
American Journal of Transplantation. 18:1408-1414
Publication Year :
2018
Publisher :
Elsevier BV, 2018.

Abstract

Evidence is currently lacking regarding the outcomes of kidneys undergoing hypothermic machine perfusion (HMP) in patients in the United Kingdom. Using the National Health Service Blood and Transplant database, the authors compared outcomes for recipients of single-organ donation after circulatory death (DCD) kidneys preserved with HMP with those preserved using only static cold storage (SCS). Between 2007 and 2015, HMP was used in 19.1% (864/4,529) of kidneys. Rates of delayed graft function (DGF) were significantly lower in organs preserved with HMP than for organs preserved with SCS (34.2% vs 42.0%, P

Details

ISSN :
16006135
Volume :
18
Database :
OpenAIRE
Journal :
American Journal of Transplantation
Accession number :
edsair.doi.dedup.....9c2ebf2b0bc1ef89f0aba4d357caa9fa
Full Text :
https://doi.org/10.1111/ajt.14587