Back to Search
Start Over
Outcomes of donation after circulatory death kidneys undergoing hypothermic machine perfusion following static cold storage: A UK population-based cohort study
- Source :
- American Journal of Transplantation. 18:1408-1414
- Publication Year :
- 2018
- Publisher :
- Elsevier BV, 2018.
-
Abstract
- Evidence is currently lacking regarding the outcomes of kidneys undergoing hypothermic machine perfusion (HMP) in patients in the United Kingdom. Using the National Health Service Blood and Transplant database, the authors compared outcomes for recipients of single-organ donation after circulatory death (DCD) kidneys preserved with HMP with those preserved using only static cold storage (SCS). Between 2007 and 2015, HMP was used in 19.1% (864/4,529) of kidneys. Rates of delayed graft function (DGF) were significantly lower in organs preserved with HMP than for organs preserved with SCS (34.2% vs 42.0%, P
- Subjects :
- Adult
medicine.medical_specialty
Tissue and Organ Procurement
animal structures
030232 urology & nephrology
Urology
Delayed Graft Function
Cold storage
030230 surgery
03 medical and health sciences
chemistry.chemical_compound
Population based cohort
0302 clinical medicine
medicine
Humans
Immunology and Allergy
Pharmacology (medical)
Transplantation
Creatinine
Machine perfusion
business.industry
Cold Ischemia
Graft Survival
Organ Preservation
Odds ratio
Middle Aged
Survival Analysis
Circulatory death
United Kingdom
Confidence interval
Surgery
chemistry
Donation
business
Subjects
Details
- ISSN :
- 16006135
- Volume :
- 18
- Database :
- OpenAIRE
- Journal :
- American Journal of Transplantation
- Accession number :
- edsair.doi.dedup.....9c2ebf2b0bc1ef89f0aba4d357caa9fa
- Full Text :
- https://doi.org/10.1111/ajt.14587