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Metabotropic glutamate receptors: an original family of G protein-coupled receptors
- Source :
- Fundamentalclinical pharmacology. 7(9)
- Publication Year :
- 1993
-
Abstract
- In 1985, we discovered a new glutamate receptor which was coupled to phospholipase C via a G protein and which was later termed metabotropic glutamate receptor (mGluR). In this review, both the diversity of mGluRs and the cellular events they control are discussed, as well as their roles in physiological regulation and brain function.
- Subjects :
- Pharmacology
Metabotropic glutamate receptor 5
musculoskeletal, neural, and ocular physiology
Metabotropic glutamate receptor 4
Metabotropic glutamate receptor 7
Metabotropic glutamate receptor 6
Brain
Biology
nervous system
Biochemistry
Receptors, Glutamate
Metabotropic glutamate receptor
GTP-Binding Proteins
Type C Phospholipases
mental disorders
Metabotropic glutamate receptor 1
Animals
Pharmacology (medical)
Metabotropic glutamate receptor 3
Metabotropic glutamate receptor 2
Protein Binding
Subjects
Details
- ISSN :
- 07673981
- Volume :
- 7
- Issue :
- 9
- Database :
- OpenAIRE
- Journal :
- Fundamentalclinical pharmacology
- Accession number :
- edsair.doi.dedup.....9c1bde29d3db303ac4eefdcf16be65f9