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Clinical Outcomes among Diagnostic Subgroups of Infants with Severe Bronchopulmonary Dysplasia through 2 Years of Age
- Source :
- American journal of perinatology. 35(14)
- Publication Year :
- 2018
-
Abstract
- Objective This article aimed to identify readmission risk factors through 2 years of life for infants with severe bronchopulmonary dysplasia (BPD) who do not require tracheostomy and ventilatory support after neonatal intensive care unit (NICU) discharge. It also aimed to identify if clinical differences exist between the subcategories of severe BPD. Study Design A retrospective chart review was performed on 182 infants with severe BPD born between 2010 and 2015. A total of 130 infants met the inclusion criteria and were stratified into three groups based on their respiratory status at 36 weeks of gestational age: group A—oxygen (O2), group B—assisted ventilation (AV), group C—both O2 and AV. NICU clinical risk factors for readmission were assessed at set time points (6/12/18/24 months). Reasons for readmission were assessed for the entire cohort and severe BPD subgroups. Conclusion An NICU diagnosis of neurologic abnormality, necrotizing enterocolitis, invasive NICU infection, dysphagia, and O2 at NICU discharge differed between the three subgroups of severe BPD. The most common cause of readmission was viral respiratory tract infection. Inhaled steroid use remained stable over time, while oxygen use and diuretic use declined over time. Risk factors for readmission in the entire cohort included g-tube, O2 use, and diuretic use at 12 months. There was no significant difference in readmission rates between the three BPD subgroups.
- Subjects :
- Male
Pediatrics
medicine.medical_specialty
Neonatal intensive care unit
Databases, Factual
Gestational Age
Patient Readmission
Positive-Pressure Respiration
03 medical and health sciences
0302 clinical medicine
Viral Respiratory Tract Infection
Risk Factors
030225 pediatrics
Intensive Care Units, Neonatal
medicine
Humans
Infant, Very Low Birth Weight
030212 general & internal medicine
Respiratory Tract Infections
Bronchopulmonary Dysplasia
Retrospective Studies
Missouri
business.industry
Infant, Newborn
Obstetrics and Gynecology
Gestational age
Infant
Retrospective cohort study
medicine.disease
Dysphagia
Patient Discharge
Oxygen
Logistic Models
Child, Preschool
Pediatrics, Perinatology and Child Health
Cohort
Necrotizing enterocolitis
Breathing
Female
medicine.symptom
business
Infant, Premature
Subjects
Details
- ISSN :
- 10988785
- Volume :
- 35
- Issue :
- 14
- Database :
- OpenAIRE
- Journal :
- American journal of perinatology
- Accession number :
- edsair.doi.dedup.....9c0b6f43511d16f65ccd7bab82e1d7c8