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Uveitis in Adult Patients with Rheumatic Inflammatory Autoimmune Diseases at a Tertiary-care Hospital in Mexico City
- Source :
- The Journal of Rheumatology. 38:325-330
- Publication Year :
- 2010
- Publisher :
- The Journal of Rheumatology, 2010.
-
Abstract
- Objective.Our aim is to describe the frequency of uveitis associated with rheumatic inflammatory autoimmune diseases (RIAD) in adult patients admitted to the Rheumatology Department at a tertiary-care hospital in Mexico City. We also describe the clinical features, seasonal distribution, treatment, and ocular complications associated with this disease.Methods.We reviewed 1332 charts of patients with RIAD and selected those that had a diagnosis of uveitis. We obtained the following data: age, sex, type of uveitis and relationship with diagnosis of RIAD, recurrences, seasonal distribution, treatment, and residual visual deficit.Results.We found 57 (4.27%) cases of uveitis in 1332 charts, including 38 men and 19 women (M:F ratio 2:1), aged 47 ± 16 years. Nongranulomatous acute anterior uveitis (NGAAU) comprised 90.52% of cases (52/57). In 64.91% of cases (37/57), uveitis preceded the diagnosis of RIAD by 12 ± 9 years, more frequently in winter (35.96%; p = NS). Uveitis was found in 40/93 patients with ankylosing spondylitis (AS), in 7/11 patients with relapsing polychondritis (RP), in 8/16 patients with Behçet’s disease, in 1/16 patients with polyarteritis nodosa, and in 1/590 patients with rheumatoid arthritis (RA). Ninety-six percent of the patients were treated with steroids. Upon a mean followup of 60 days (range 7–4745 days), reduction of visual acuity (≤ 20/200) was associated with recurrence of uveitis in 3/7 cases with AS, in 4/8 cases with Behçet’s disease, in 3/7 with RP, and in 1 case of uveitis and seronegative RA.Conclusion.NGAAU frequently precedes RIAD and is found predominately in men, with a tendency to occur in winter.
- Subjects :
- Adult
Male
medicine.medical_specialty
Systemic disease
Adolescent
Immunology
Autoimmune Diseases
Uveitis
Rheumatology
Rheumatic Diseases
Internal medicine
medicine
Humans
Immunology and Allergy
Child
Mexico
Relapsing polychondritis
Aged
Inflammation
Ankylosing spondylitis
Polyarteritis nodosa
business.industry
Middle Aged
medicine.disease
Dermatology
Surgery
Rheumatoid arthritis
Female
business
Vasculitis
Subjects
Details
- ISSN :
- 14992752 and 0315162X
- Volume :
- 38
- Database :
- OpenAIRE
- Journal :
- The Journal of Rheumatology
- Accession number :
- edsair.doi.dedup.....9c033b1014571f251360b2f3129f4826