Supplementary Figure S2 from Radioprotection of IDH1-Mutated Cancer Cells by the IDH1-Mutant Inhibitor AGI-5198

Authors :: Cornelis J. van Noorden
Fonnet E. Bleeker
William P. Leenders
W. Peter Vandertop
Jaroslaw P. Maciejewski
Johanna W. Wilmink
Tomas Radivoyevitch
Ron A. Hoebe
Cornelis M. van Drunen
Dionysia Dimitrakopoulou
Adri N. Mul
Krissie Lenting
Mohammed Khurshed
Peter Henneman
Jan Stap
Sanne A. van Lith
Vashendriya V. Hira
Myrthe A. Smits
Dennis Botman
Remco J. Molenaar
Publication Year :: 2023
Publisher :: American Association for Cancer Research (AACR), 2023.
Abstract: D-2HG inhibits IDH-mediated NADPH production capacity, but not G6PD-mediated NADPH production capacity or IDH-mediated NADH production capacity.

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