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Synergistic Effect of History of Cardiovascular Disease and Mental Distress on Post-Traumatic Stress Disorder after the Great East Japan Earthquake: The Fukushima Health Management Survey
- Source :
- International Journal of Environmental Research and Public Health, Vol 18, Iss 10283, p 10283 (2021), International Journal of Environmental Research and Public Health, Volume 18, Issue 19
- Publication Year :
- 2021
- Publisher :
- MDPI AG, 2021.
-
Abstract
- Cardiovascular disease (CVD) and mental distress have been suggested to be associated with post-traumatic stress disorder (PTSD), but the effect of their combination on PTSD is unknown. We reviewed the synergistic effects of the history of CVD and mental distress on the possibility of PTSD among residents in Fukushima after the Great East Japan Earthquake. This cross-sectional study was conducted among 38,392 participants aged 40–74 years in the evacuation area who applied for the Fukushima Health Management Study in Fiscal Year 2011. Relative excess risk due to interaction (RERI), attributable proportion (AP), odds ratio (OR), and 95% confidence interval (CI) were calculated to investigate the combined effect of history of CVD and mental distress on PTSD. We identified 8104 probable cases of PTSD (21.1%). History of CVD, mental distress, and their combination were positively associated with probable PTSD: the multivariable ORs (95% CIs) were 1.44 (1.04, 2.01), 20.08 (18.14, 22.22), and 26.60 (23.07, 30.67), respectively. There was a significant increase in RERI: the corresponding RERI (95% CI) and AP were 6.08 (3.16, 9.00) and 22.9%. Gender-specific analyses showed similar associations. Thus, we found a supra-additive association of history of CVD and mental distress with probable PTSD after the disaster.
- Subjects :
- Adult
Health, Toxicology and Mutagenesis
Disease
Article
Stress Disorders, Post-Traumatic
Mental distress
Japan
cardiovascular disease
mental distress
attributable proportion
mental disorders
Earthquakes
Fukushima Nuclear Accident
Humans
Medicine
Aged
the Great East Japan Earthquake
the relative excess risk due to interaction
Health management system
business.industry
Public Health, Environmental and Occupational Health
Traumatic stress
Absolute risk reduction
Odds ratio
Middle Aged
Confidence interval
Cross-Sectional Studies
Cardiovascular Diseases
post-traumatic stress disorder
business
Demography
Subjects
Details
- Language :
- English
- ISSN :
- 16617827 and 16604601
- Volume :
- 18
- Issue :
- 10283
- Database :
- OpenAIRE
- Journal :
- International Journal of Environmental Research and Public Health
- Accession number :
- edsair.doi.dedup.....9bfab6cef1799bdca012945ff148bb10