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Role of advanced MR imaging modalities in diagnosing cerebral gliomas
- Publication Year :
- 2009
-
Abstract
- The objective of this study was to evaluate the potential role of newly developed, advanced magnetic resonance (MR) imaging techniques (spectroscopy, diffusion and perfusion imaging) in diagnosing brain gliomas, with special reference to histological typing and grading, treatment planning and posttreatment follow-up. Conventional MR imaging enables the detection and localisation of neoplastic lesions, as well as providing, in typical cases, some indication about their nature. However, it has limited sensitivity and specificity in evaluating histological type and grade, delineating margins and differentiating oedema, tumour and treatment side-effects. These limitations can be overcome by supplementing the morphological data obtained with conventional MR imaging with the metabolic, structural and perfusional information provided by new MR techniques that are increasingly becoming an integral part of routine MR studies. Incorporation of such new MR techniques can lead to more comprehensive and precise diagnoses that can better assist surgeons in determining prognosis and planning treatment strategies. In addition, the recent development of new, more effective, treatments for cerebral glioma strongly relies on morphofunctional MR imaging with its ability to provide a biological interpretation of these characteristically heterogeneous tumours.
- Subjects :
- medicine.medical_specialty
Magnetic Resonance Spectroscopy
Interventional magnetic resonance imaging
Perfusion scanning
Sensitivity and Specificity
Patient Care Planning
medicine
Humans
Radiology, Nuclear Medicine and imaging
Radiation treatment planning
Grading (tumors)
Neuroradiology
medicine.diagnostic_test
Brain Neoplasms
business.industry
Magnetic resonance spectroscopic imaging
Magnetic resonance imaging
Glioma
General Medicine
Magnetic Resonance Imaging
Diffusion Magnetic Resonance Imaging
Radiology
business
Magnetic Resonance Angiography
Preclinical imaging
Follow-Up Studies
Subjects
Details
- Database :
- OpenAIRE
- Accession number :
- edsair.doi.dedup.....9bb9a672d93b83d1ca540df163c1efca