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DNA detection with a polymeric nanochannel device
- Source :
- Lab on a chip. 11(17)
- Publication Year :
- 2011
-
Abstract
- We present the development and the electrical characterization of a polymeric nanochannel device. Standard microfabrication coupled to Focused Ion Beam (FIB) nanofabrication is used to fabricate a silicon master, which can be then replicated in a polymeric material by soft lithography. Such an elastomeric nanochannel device is used to study DNA translocation events during electrophoresis experiments. Our results demonstrate that an easy and low cost fabrication technique allows creation of a low noise device for single molecule analysis.
- Subjects :
- Electrophoresis
Silicon
Materials science
Fabrication
Biomedical Engineering
chemistry.chemical_element
Bioengineering
Nanotechnology
General Chemistry
DNA
Elastomer
Biochemistry
Focused ion beam
Soft lithography
Characterization (materials science)
Nanostructures
Nanolithography
chemistry
Dimethylpolysiloxanes
Microfabrication
Subjects
Details
- ISSN :
- 14730189
- Volume :
- 11
- Issue :
- 17
- Database :
- OpenAIRE
- Journal :
- Lab on a chip
- Accession number :
- edsair.doi.dedup.....9bac8b0055517bb3d58dfb39c58a6040