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Management of quinolone-resistant typhoid osteomyelitis

Authors :
Darius Armstrong-James
Stephen Morris-Jones
Emily Pollock
Julie Lau Kuen Wing
Alastair McGregor
Michael Brown
Source :
British journal of hospital medicine (London, England : 2005). 72(8)
Publication Year :
2011

Abstract

andtrimethoprim-sulfamethoxazole,� whicharetraditionallyfirst-lineagentsfor� thetreatmentofentericfever.�Themultid- rugresistancephenotypehasbecomecom- moninS. typhiand,�toalesserextent,�S. paratyphi� (ParryandThrelfall,� 2008)� and� thishasledtogreaterrelianceonother� agents,�particularlyfluoroquinolones.� Promisingresultswithciprofloxacin� suggestedthatitwasmoreeffectiveinthe� treatmentofuncomplicatedentericfever� inareaswithhighratesofmultidrugresist- ancesalmonellae� (Alametal,� 1995)� and� quinolonesalsohavesignificantlyreduced� failureratescomparedwithsomefirst-line� agentsinentericfevercausedbysuscepti- bleisolates� (Thaveretal,� 2008).� Unfortunately,� overthepastdecade,� iso- lateswithdecreasedciprofloxacinsuscepti- bilityhavebecomemorecommonandare� associatedwithtreatmentfailureand� relapse� (Chuangetal,� 2009).� Atthe� HospitalforTropicalDiseases,� London,� salmonellaewithdecreasedciprofloxacin�

Details

ISSN :
17508460
Volume :
72
Issue :
8
Database :
OpenAIRE
Journal :
British journal of hospital medicine (London, England : 2005)
Accession number :
edsair.doi.dedup.....9b8fb1e94ab4ab82bddb05330459d6cb