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Aortic Neck Anatomic Features and Predictors of Outcomes in Endovascular Repair of Abdominal Aortic Aneurysms Following vs Not Following Instructions for Use
- Source :
- Journal of the American College of Surgeons. 222:579-589
- Publication Year :
- 2016
- Publisher :
- Ovid Technologies (Wolters Kluwer Health), 2016.
-
Abstract
- A significant number of patients undergo endovascular repair of abdominal aortic aneurysms (EVAR) outside the instructions for use (IFU). This study will examine various aortic neck features and their predictors of clinical outcomes.We performed a retrospective analysis of prospectively collected data on EVAR patients. Neck features outside IFU were analyzed. Kaplan-Meier and multivariate analyses were used to predict their effect as single features, or in combination, on outcomes.Fifty-two percent of 526 patients had 1 or more features outside the IFU. The overall technical success rate was 99%, and perioperative complication rates were 7% and 12% for IFU vs outside IFU use, respectively (p = 0.04). Type I early endoleak and early intervention rates were 7% and 10% for IFU vs 18% and 24% for outside IFU (p = 0.0002 and p0.0001). At a mean follow-up of 30 months, freedom from late type I endoleak and late reintervention at 1, 2, and 3 years for IFU were 99.5%, 99.5%, and 98.4%, and 99.4%, 98%, and 96.8%; vs 98.9%, 98.1%, and 98.1%, and 97.5%, 96.2%, and 95.2% for outside IFU (p = 0.049 and 0.799), respectively. Survival rates at 1, 2, and 3 years for IFU were 97%, 93.5%, and 89.8%; vs 93.7%, 88.8%, and 86.3% for outside IFU (p = 0.035). Multivariate analysis showed that a neck angle60 degrees had odds ratios for death, sac expansion, and early intervention of 6, 2.6, and 3.3, respectively; neck length10 mm had odds ratios of 2.8 for deaths, 3.4 for early intervention, 4.6 for late reintervention, and 4.3 for late type I endoleak.Patients with neck features outside IFU can be treated with EVAR; however, they have higher rates of early and late type I endoleak, early intervention, and late death.
- Subjects :
- Male
medicine.medical_specialty
Endoleak
Kaplan-Meier Estimate
030204 cardiovascular system & hematology
Article
Blood Vessel Prosthesis Implantation
03 medical and health sciences
Aortic aneurysm
0302 clinical medicine
Blood vessel prosthesis
Odds Ratio
medicine
Humans
030212 general & internal medicine
Aged
Retrospective Studies
Aged, 80 and over
business.industry
Patient Selection
Endovascular Procedures
Retrospective cohort study
Odds ratio
Perioperative
medicine.disease
Abdominal aortic aneurysm
Blood Vessel Prosthesis
Surgery
Treatment Outcome
Female
Radiology
Complication
business
Aortic Aneurysm, Abdominal
Abdominal surgery
Subjects
Details
- ISSN :
- 10727515
- Volume :
- 222
- Database :
- OpenAIRE
- Journal :
- Journal of the American College of Surgeons
- Accession number :
- edsair.doi.dedup.....9b87dda9fa389b22db61256cbb6c5d15