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Identification and characterization of Lyc e 4, a Bet v 1 homologous PR-10 protein, in tomato fruits
- Source :
- Clinical and Translational Allergy
- Publisher :
- Springer Nature
-
Abstract
- Background Allergy to tomato (Lycopersicon esculentum) has been reported to occur in 3-16% of food allergic subjects. Tomato allergy is frequently manifested as OAS, urticaria and gastrointestinal symptoms. So far, three tomato allergens, Lyc e 1 (profilin), Lyc e 2 (invertase) and Lyc e 3 (nsLTP) are listed in the official IUIS allergen database. Although tomato allergy is frequently associated with birch pollen allergy in Central Europe, a cross-reactive Bet v 1 homologous allergen has not yet been described in tomato fruits. The objective of the present study was the cDNA cloning, recombinant expression and immunological characterization of Bet v 1 homologous PR10-proteins from tomato fruits.
- Subjects :
- Pulmonary and Respiratory Medicine
Cdna cloning
Allergy
biology
Recombinant expression
business.industry
fungi
Immunology
food and beverages
biology.organism_classification
medicine.disease
medicine.disease_cause
Lycopersicon
Microbiology
Allergen
Invertase
Profilin
Poster Presentation
biology.protein
Homologous chromosome
Immunology and Allergy
Medicine
ddc:610
business
Subjects
Details
- Language :
- English
- ISSN :
- 20457022
- Volume :
- 3
- Issue :
- Suppl 3
- Database :
- OpenAIRE
- Journal :
- Clinical and Translational Allergy
- Accession number :
- edsair.doi.dedup.....9b804c134321bb27096d1c3fbb83a87a
- Full Text :
- https://doi.org/10.1186/2045-7022-3-s3-p87