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Reference Curves for the Aortic Area by Age
- Source :
- Academic Radiology. 20:16-24
- Publication Year :
- 2013
- Publisher :
- Elsevier BV, 2013.
-
Abstract
- The aim of this study was to establish reference curves and formulas for aortic cross-sectional area in patients from infancy to young adulthood.Patients (aged 2 days to 18.1 years) who underwent electrocardiographically gated cardiac computed tomography between May 2004 and December 2011 were retrospectively examined. These patients were further divided into a group of normal controls (without aortic disease) and a group with coarctation of aorta. In the group of normal controls, the cross-sectional area of the aorta was measured at six locations: the sinotubular junction, distal ascending aorta, proximal arch, distal arch, aortic isthmus, and descending aorta (DAO). Interobserver and intraobserver variability, gender differences, the relationship between aortic cross-sectional areas and age, and the ratio to the DAO were also examined. The area ratio to the DAO was also examined in the group with coarctation of the aorta.A total of 65 patients and 365 measurable aortic segments were included in the analysis (55 normal controls and 10 patients with coarctation of aorta). Interobserver and intraobserver variability was limited (aside from measurements of the sinotubular junction). There were no gender differences in age and the cross-sectional areas of the different aortic segments. In the group of normal controls, the cross-sectional area of each aortic segment was highly correlated with age (all0.90, P.001). The reference curves and formulas for aortic cross-sectional area by age were also determined for further clinical use. In the normal controls, the95% confidence intervals of the ratios of aortic isthmus to DAO, distal arch to DAO, and proximal arch to DAO were approximately 0.6, 0.8, and 1.0, respectively. In addition, in the group with coarctation, all area ratios of aortic isthmus to DAO were0.6, which was significantly different from the group of normal controls (P.001). The area ratios of distal arch to DAO and proximal arch to DAO were also significantly different between two groups (P.001 for both).Measurement of aortic area was reproducible. The established reference curves and formulas and minimal area ratios were convenient for further clinical use.
- Subjects :
- Male
medicine.medical_specialty
Adolescent
Iohexol
Cardiac-Gated Imaging Techniques
Coarctation of the aorta
Contrast Media
Aortic area
Aortic Coarctation
Reference Values
medicine.artery
Internal medicine
Ascending aorta
medicine
Humans
Radiology, Nuclear Medicine and imaging
Young adult
Child
Aorta
Retrospective Studies
Aortic Segment
Anatomy, Cross-Sectional
business.industry
Sinotubular Junction
Age Factors
Infant, Newborn
Infant
medicine.disease
Case-Control Studies
Child, Preschool
Descending aorta
Linear Models
cardiovascular system
Cardiology
Radiographic Image Interpretation, Computer-Assisted
Female
Tomography, X-Ray Computed
business
Subjects
Details
- ISSN :
- 10766332
- Volume :
- 20
- Database :
- OpenAIRE
- Journal :
- Academic Radiology
- Accession number :
- edsair.doi.dedup.....9b6e8a5e422a79a8ea803d3e7ab6925c