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Does Oxybutynin Hydrochloride Cause Arrhythmia in Children with Bladder Dysfunction?
- Source :
- Medical Archives. 67:202
- Publication Year :
- 2013
- Publisher :
- ScopeMed, 2013.
-
Abstract
- Aim: Pediatric surgeons frequently encounter children presenting with voiding dysfunction symptoms, including urgency, frequency, and incontinence. Antimuscarinic agents (Oxybutynin) are the main drugs used to treat patients with overactive bladder (OAB) syndrome, defined as urgency, with or without urgency incontinence, usually with increased daytime frequency and nocturia. Increased QT dispersion is known to be the cause of ventricular arrhythmia in various systemic diseases and leads to increased mortality and morbidity. Method: This study represents a subset of a complete data set, considering only those children aged admitted to the Pediatric Surgery and Pediatric Nephrology Clinics during the period January 2011 to July 2012. Result: In this study, we have determined that the QT interval changes significantly depending on the use of oxybutynin. The QT changes increased cardiac arrhythmia in children. Conclusion: For this reason, children using such drugs should be closely monitored for cardiac arrhythmia.
- Subjects :
- Male
medicine.medical_specialty
Pediatrics
Adolescent
Muscarinic Antagonists
QT interval
Electrocardiography
Pediatric surgery
medicine
Humans
Nocturia
Child
Oxybutynin
Retrospective Studies
Urinary bladder
Urinary Bladder, Overactive
business.industry
Cardiac arrhythmia
Arrhythmias, Cardiac
Retrospective cohort study
General Medicine
medicine.disease
medicine.anatomical_structure
Overactive bladder
Child, Preschool
Mandelic Acids
Female
medicine.symptom
business
medicine.drug
Subjects
Details
- ISSN :
- 0350199X
- Volume :
- 67
- Database :
- OpenAIRE
- Journal :
- Medical Archives
- Accession number :
- edsair.doi.dedup.....9b4ddc779c7b3caf1c8ffcb7711d185c