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Injection lipolysis for reduction of saddlebag trochanteric bulges--half-side controlled pilot study
- Source :
- Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG. 6(4)
- Publication Year :
- 2007
-
Abstract
- Summary Background: Phosphatidylcholine, a lecithin extracted from soybeans can reduce serum cholesterol to some extent. Intravenous use may prevent fat embolism in polytrauma patients. When injected intralesionally in a formulation containing also deoxycholate and ethanol it is supposed to act as “fat burner” to reduce undesired fat deposits; there is little evidence-based scientific support for this indictaion. Objective: To evaluate the capability of phosphatidylcholin + deoxycholate + ethanol (PPC/DC/E) to reduce body fat with a half-side pilot study for the reduction of saddlebag trochanteric bulges. Methods: PPC/DC/E was injected into the right posterior trochanteric areas three times at weeks 0, 3 and 6. Treatment areas and the same regions of the contralateral side as a control were evaluated by sonography. Tape measurements were taken and the thickness of the subcutaneous adipose tissue (SAT) was measured with an optical device (Lipometer®) at baseline and at week 8 and week 20 (2 and 14 weeks after completign therapy). Results: In this half-side trial, no significant reduction of subcutaneous fat was achieved after three treatments with PPC/DC/E when compared to the untreated side.Transient inflammatory reactions occurred in all patients. Limitations: Only the commercially available formulation containing the three components was tested. Conclusion: The off-label use of PPC/DC/E as a “fat burner” did not produce measurable reduction of undesired trochanteric fat deposits.
- Subjects :
- Adult
medicine.medical_specialty
food.ingredient
medicine.medical_treatment
Injections, Subcutaneous
Lipolysis
Urology
Pilot Projects
Dermatology
Injection lipolysis
Cosmetic Techniques
Subcutaneous fat
Lecithin
Body Mass Index
chemistry.chemical_compound
food
Phosphatidylcholine
medicine
Humans
Tomography, Optical
Fat embolism
Reduction (orthopedic surgery)
business.industry
Middle Aged
medicine.disease
Surgery
Drug Combinations
Skinfold Thickness
chemistry
Adipose Tissue
Thigh
Right posterior
Phosphatidylcholines
Female
Subcutaneous adipose tissue
business
Subjects
Details
- Language :
- German
- ISSN :
- 16100387
- Volume :
- 6
- Issue :
- 4
- Database :
- OpenAIRE
- Journal :
- Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG
- Accession number :
- edsair.doi.dedup.....9b2d0f3abb74ca88e79781a1f4597491