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Severe Obesity as an Independent Risk Factor for COVID-19 Mortality in Hospitalized Patients Younger than 50
- Source :
- Obesity (Silver Spring, Md.), Obesity
- Publication Year :
- 2020
-
Abstract
- OBJECTIVE: Coronavirus disease 2019 (COVID-19) continues to spread, and younger patients are also being critically affected. This study analyzed obesity as an independent risk factor for mortality in hospitalized patients younger than 50. METHODS: This study retrospectively analyzed data of patients with COVID-19 who were hospitalized to a large academic hospital system in New York City between March 1, 2020, and May 17, 2020. Data included demographics, comorbidities, BMI, and smoking status. Obesity groups included the following: BMI of 30 to < 40 kg/m2 and BMI ≥ 40 kg/m2 . Multivariable logistic regression models identified variables independently associated with mortality in patients younger and older than 50. RESULTS: Overall, 3,406 patients were included; 572 (17.0%) patients were younger than 50. In the younger age group, 60 (10.5%) patients died. In the older age group, 1,076 (38.0%) patients died. For the younger population, BMI ≥ 40 was independently associated with mortality (adjusted odds ratio 5.1; 95% CI: 2.3-11.1). For the older population, BMI ≥ 40 was also independently associated with mortality to a lesser extent (adjusted odds ratio 1.6; 95% CI: 1.2-2.3). CONCLUSIONS: This study demonstrates that hospitalized patients younger than 50 with severe obesity are more likely to die of COVID-19. This is particularly relevant in the Western world, where obesity rates are high.
- Subjects :
- Adult
Male
medicine.medical_specialty
obesity
Coronavirus disease 2019 (COVID-19)
Endocrinology, Diabetes and Metabolism
Population
Pneumonia, Viral
Medicine (miscellaneous)
030209 endocrinology & metabolism
Comorbidity
Logistic regression
SARS‐CoV‐2
03 medical and health sciences
Betacoronavirus
0302 clinical medicine
Endocrinology
Risk Factors
COVID‐19
Internal medicine
Odds Ratio
Medicine
Humans
030212 general & internal medicine
Risk factor
education
Pandemics
Aged
Retrospective Studies
Brief Cutting Edge Report
education.field_of_study
Nutrition and Dietetics
business.industry
SARS-CoV-2
COVID-19
Retrospective cohort study
Odds ratio
Middle Aged
medicine.disease
Obesity
mortality
Obesity, Morbid
Hospitalization
Logistic Models
Brief Cutting Edge Reports
Female
business
Coronavirus Infections
Subjects
Details
- ISSN :
- 1930739X
- Volume :
- 28
- Issue :
- 9
- Database :
- OpenAIRE
- Journal :
- Obesity (Silver Spring, Md.)
- Accession number :
- edsair.doi.dedup.....9b2c205db9c6c6a40bca69f31a0a4370