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Posterior Reversible Leukoencephalopathy Syndrome in a Patient after Acute COVID-19 Infection
- Source :
- Case Reports in Neurological Medicine, Vol 2021 (2021), Case Reports in Neurological Medicine
- Publication Year :
- 2021
- Publisher :
- Hindawi Limited, 2021.
-
Abstract
- The SARS-CoV-2 infection affects numerous organs, including the central nervous system. The neuroinvasive abilities and neuroinflammation may lead to short- and long-term neurological manifestations. Among neurological disorders associated with SARS-CoV-2 infection, posterior reversible encephalopathy syndrome (PRES) has been described in a few case-based observational studies during the acute phase of COVID-19 hospitalization. We present a case of a patient who developed seizures and PRES after recovering from an acute severe COVID-19 infection.A 90-year-old African American female with multiple comorbidities and a severe COVID-19 infection was discharged home in stable condition after two weeks of hospitalization. A week later, she developed new-onset generalized tonic-clonic seizures requiring readmission to the hospital. The patient’s clinical course and brain imaging supported PRES. Her mentation returned to baseline with supportive care and anticonvulsant treatment. Follow-up brain MRI four months later demonstrated resolution of FLAIR signal abnormalities confirming PRES. SARS-CoV-2 insult on the cerebrovascular endothelial cells likely continued and despite the clinical recovery eventually resulted in PRES. We believe that this is the first case describing the presentation of PRES after recovery from severe acute COVID-19 infection.
- Subjects :
- Pediatrics
medicine.medical_specialty
Coronavirus disease 2019 (COVID-19)
business.industry
medicine.medical_treatment
Central nervous system
Case Report
Posterior reversible encephalopathy syndrome
Fluid-attenuated inversion recovery
medicine.disease
Leukoencephalopathy
medicine.anatomical_structure
Anticonvulsant
Neuroimaging
medicine
Neurology. Diseases of the nervous system
General Agricultural and Biological Sciences
business
RC346-429
Neuroinflammation
Subjects
Details
- Language :
- English
- ISSN :
- 20906676 and 20906668
- Volume :
- 2021
- Database :
- OpenAIRE
- Journal :
- Case Reports in Neurological Medicine
- Accession number :
- edsair.doi.dedup.....9acb25cd0d429eac4736f835c67231d5