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Neoangiogenesis is Reduced in Chronic Tendinopathies and Type 2 Diabetic Patients
- Source :
- International Journal of Immunopathology and Pharmacology. 25:757-761
- Publication Year :
- 2012
- Publisher :
- SAGE Publications, 2012.
-
Abstract
- In diabetes, the prevalence of tendon degeneration is increased. As neoangiogenesis is impaired in several diabetic complications, the aim of this study is to evaluate the neovessel formation in tendinopathies. Patients aged > 55 years were selected, and divided into two groups: a) type 2 diabetic patients, and b) non-diabetic subjects. In both groups, those with ultrasound features of tendinopathy were included, and intratendinous vascularisation was estimated by means of Power Doppler. Ultrasound features of tendinopathy were observed in 104 diabetic subjects and in 221 controls. Neovascularisation, with higher Power Doppler scores, was found more frequently in controls, while lower Power Doppler scores were prevalent in diabetic subjects. In subjects with diabetes, tendinopathic features are significantly higher than healthy controls, while the prevalence of neovascularization inside tendons is less represented. Copyright © by BIOLIFE, s.a.s. In diabetes, the prevalence of tendon degeneration is increased. As neoangiogenesis is impaired in several diabetic complications, the aim of this study is to evaluate the neovessel formation in tendinopathies. Patients aged > 55 years were selected, and divided into two groups: a) type 2 diabetic patients, and b) non-diabetic subjects. In both groups, those with ultrasound features of tendinopathy were included, and intratendinous vascularisation was estimated by means of Power Doppler. Ultrasound features of tendinopathy were observed in 104 diabetic subjects and in 221 controls. Neovascularisation, with higher Power Doppler scores, was found more frequently in controls, while lower Power Doppler scores were prevalent in diabetic subjects. In subjects with diabetes, tendinopathic features are significantly higher than healthy controls, while the prevalence of neovascularization inside tendons is less represented. Copyright © by BIOLIFE, s.a.s.
- Subjects :
- Male
medicine.medical_specialty
Blood Vessel
Immunology
Degeneration (medical)
Diabete
Diabetes Complications
Tendons
Neovascularization
Power doppler
chemistry.chemical_compound
Retrospective Studie
Diabetes Complication
Diabetes mellitus
Internal medicine
medicine
Humans
Immunology and Allergy
Tendon
Retrospective Studies
Ultrasonography
Aged
Pharmacology
Neovascularization, Pathologic
business.industry
Ultrasound
Ultrasonography, Doppler
Middle Aged
medicine.disease
Neoangiogenesi
Vascular endothelial growth factor
medicine.anatomical_structure
Diabetes Mellitus, Type 2
Italy
chemistry
Tendinopathy
Chronic Disease
Cardiology
Blood Vessels
Female
medicine.symptom
business
Human
Subjects
Details
- ISSN :
- 20587384
- Volume :
- 25
- Database :
- OpenAIRE
- Journal :
- International Journal of Immunopathology and Pharmacology
- Accession number :
- edsair.doi.dedup.....9ac7ec267611586c5ac130fe9ea8c027