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Do Younger Women Fare Worse? Sex Differences in Acute Myocardial Infarction Hospitalization and Early Mortality Rates Over Ten Years
- Source :
- Journal of Women's Health. 23:10-17
- Publication Year :
- 2014
- Publisher :
- Mary Ann Liebert Inc, 2014.
-
Abstract
- Recent research has identified younger women as an "at-risk" population with rising prevalence of cardiac risk factors and excess mortality risk following acute myocardial infarction (AMI). However, population-based data on trends in AMI hospitalization and early mortality post AMI among younger adults is scarce. We, therefore, aimed to provide a 10-year, descriptive analysis of these trends in a Canadian setting.We assessed trends and sex differences in AMI hospitalization and 30-day mortality rates using negative binomial and logistic regression, respectively. From 2000 to 2009, there were 70,628 AMI hospitalizations in adults aged ≥20 years, in British Columbia, Canada, with 17.1% of cohort being younger adults ≤55 years. Overall, age-standardized AMI rates (per 100,000 population) declined similarly in men (295.8 to 247.7) and women (152.1 to 128.8) [sex-year interaction p=0.81]. However, these trends differed according to age (age-sex-year interaction p=0.02) with increased rates observed only in younger women (+1.7% per year; p=0.04). The 30-day mortality rates declined similarly for women (19.4% to 13.9%) and men (13.0% to 9.3%) (sex-year interaction p=0.33). Yet, younger women continued to have excess mortality risk, compared with younger men, even in the most recent period [odds ratio: (2008-09)=1.61 (95% onfidence interval: 1.25, 2.08)].While the overall AMI hospitalization and 30-day mortality rates significantly declined in women and men, hospitalization rates in women ≤55 years increased and their excess risk of 30-day mortality persisted. These findings highlight the need to intensify strategies to reduce the incidence of AMI and improve outcomes after AMI in younger women.
- Subjects :
- Adult
Male
Pediatrics
medicine.medical_specialty
Population
Myocardial Infarction
Comorbidity
Logistic regression
Severity of Illness Index
Sex Factors
Risk Factors
Prevalence
medicine
Humans
Hospital Mortality
cardiovascular diseases
Sex Distribution
education
Survival rate
Aged
Retrospective Studies
Aged, 80 and over
education.field_of_study
British Columbia
business.industry
Incidence
Incidence (epidemiology)
Mortality rate
Age Factors
Retrospective cohort study
General Medicine
Middle Aged
medicine.disease
Hospitalization
Survival Rate
Logistic Models
Population Surveillance
Acute Disease
Cohort
Female
business
Demography
Subjects
Details
- ISSN :
- 1931843X and 15409996
- Volume :
- 23
- Database :
- OpenAIRE
- Journal :
- Journal of Women's Health
- Accession number :
- edsair.doi.dedup.....9ab08ae0bfb6489b9d839eb5517d8823